Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 1,8-Diazanaphthalene, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 254-60-4
Yantai Kaibo Pharmaceutical Technology Co., Ltd.; Chen Jinchun; Ma Shaohui; Sheng Jianzhang; Cui Ningning
This invention has offered a kind of preparation 1,8 the method for […] naphthyridine and derivatives, add the oxidizing agent in the acid in the formula I compound or its salt to obtain reaction liquid. Stirring and heating the reaction liquid, the reaction compounds II even instillment type, cooling to room temperature, neutralized with alkaline solution, aqueous phase extraction with a solvent to obtain the organic phase. To eliminate the concentration of the organic solvent under reduced pressure, compound of formula III. The method of the present invention overcome the Skraup synthesis of the 1,8 the naphthyridine and derivatives […] low yield and the disadvantages of high cost. (by machine translation)
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Reference£º
1,22-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N16 – PubChem