Application of 254-60-4, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.254-60-4, Name is 1,8-Diazanaphthalene, molecular formula is C8H6N2. In a article£¬once mentioned of 254-60-4
A series of 1,8-naphthyridine derivatives 3(a-g) and 4(a-g) as potential antibacterial agents were designed and efficiently amination of 2-chloro-3-aryl-1,8-naphthyridines 1(a-g) with various anilines substituents in positions two. All synthesized target compounds were characterized by 1H NMR, 13C NMR and MS spectra. All the synthesized compounds were evaluated for their anti-bacterial activity against P. aeruginosa, E.coli (Gram -ve bacteria) and S.aureus, B.subtilis (Gram +ve bacteria) in contrast with the clinical Ciprofloxacin. The molecular docking study was succeeded to understand the likely interactions with the new synthesized compounds 3(a-g) and 4(a-g). Docking investigation demonstrated that active molecule 3b, 3e and 4b, 4e, 4g have better docking score with protein.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 254-60-4
Reference£º
1,246-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N240 – PubChem