Chemistry is traditionally divided into organic and inorganic chemistry. COA of Formula: C8H6BrN3, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 5912-35-6
Quinuclidine-containing spirooxazolines, as described in the previous report in this series, were demonstrated to have utility as alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) partial agonists. In this work, the SAR of this chemotype was expanded to include an array of diazine heterocyclic substitutions. Many of the heterocyclic analogs were potent partial agonists of the alpha7 receptor, selective against other nicotinic receptors and the serotinergic 5HT3A receptor. (1?S,3?R,4?S)-N-(6-phenylpyrimidin-4-yl)-4H-1?-azaspiro[oxazole-5,3?-bicyclo[2.2.2]octan]-2-amine, a potent and selective alpha7 nAChR partial agonist, was demonstrated to improve cognition in the mouse novel object recognition (NOR) model of episodic memory.
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Reference£º
1,632-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N626 – PubChem