5912-35-6, Name is 6-Amino-8-bromo-1,7-naphthyridine, belongs to naphthyridine compound, is a common compound. HPLC of Formula: C8H6BrN3In an article, once mentioned the new application about 5912-35-6.
The synthesis of a 6,8-disubstituted 1,7-naphthyridine 1 and its characterization as a potent and selective phosphodiesterase type 4D inhibitor (IC50=1.5nM) are described. The compound inhibited TNFalpha-release from human peripheral blood mononuclear cells and was orally active in a model of adjuvant-induced arthritis in rats.
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Reference£º
1,631-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N625 – PubChem