One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C8H6N2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 254-60-4, Name is 1,8-Diazanaphthalene, molecular formula is C8H6N2
The tachykinin NK2 receptor is widel y distributed in the peripheral and central nervou s system. It mediates numerous pharmacologi cal effects of neurokinin A, suggesting that the tachykinin NK2 receptor may be possible target for new therapeutics. Many effor ts to identify and cha racterize selective antagonists of thi s receptor have been undertaken and several antagonists of both peptide and nonpeptide nature have been disclosed. Among th ese compounds, nepadutant, a peptide-based antagonist, and saredutant, a nonpeptide antagoni st, are certainly among the most potent compounds. These two antagonists combine high affinity for the human tachykinin NK2 receptor with strong antagonist activities in a large variety of in vitro and in vivo pharmacological models. Contrary to nepadutant, saredutant has been shown to be orally active. In addition to th eir potent acti vitie s in the airways they show potent inhibitory activities in visceral nociception suggesting that a tach ykinin NK2 receptor antagonist may be useful for the tre atment of functional gastrointestinal disorders such as irritable bowel syndrome. With the use of saredutant, major progress has also been made in the understanding of the role of brain tachykinin NK2 receptors. Contrary to nepadutant, saredutant is centrally active and shows antidepressant/anxiolytic activity.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, HPLC of Formula: C8H6N2, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 254-60-4
Reference£º
1,110-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N104 – PubChem