Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of 1,8-Diazanaphthalene. Introducing a new discovery about 254-60-4, Name is 1,8-Diazanaphthalene
This paper presents a new family of pyrimidine-based BF2 complexes. The series contains six examples of 1,1-difluoro-3-aryl(heteroaryl)-1H-pyrimido[1,2-c][1,3,5,2]oxadiazaborinin-9-ium-1-uides (2) ? in which aryl(heteroaryl) = phenyl, 4-MeC6H4, 4-N(CH3)2C6H4, 4-NO2C6H4, 2-naphthyl, and 2-thienyl. The heterocycles 2 were easily synthesized at yields of 50?68% from reactions ? at room temperature for 24 h ? of simple N-(pyrimidin-2-yl)benzamides (1) with BF3¡¤Et2O, and they were fully characterized by 1H-, 13C-, 19F, 11B-NMR, GC?MS, and X-ray diffractometry. Moreover, the photophysical properties, TD-DFT analysis, BSA-binding experiments, and molecular docking studies for the new organoboron complexes 2 were determined, presented, discussed, and compared with similar compounds that have already been described.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 1,8-Diazanaphthalene, you can also check out more blogs about254-60-4
Reference£º
1,76-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N70 – PubChem