The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Formula: C8H12ClN3OS, 149022-15-1, Name is 3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate(1:1:x), SMILES is CN1/C(SC2=CC=CC=C12)=N/N.[H]Cl.[H]O[H], in an article , author is Zhang, Jianqing, once mentioned of 149022-15-1.
Synthesis of 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1, 4-dihydro-1, 8-naphthyridine-3-carboxylic acid
7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1, 4-dihydro-1, 8-naphthyridine-3-carboxylic acid is an important intermediate for the many biologically active anticancer drugs. In this research, a rapid and efficient synthesis of compounds 7 was established. Compound 7 consisting of methyl (Z)-2-(2, 5-dichloro-6-fluoronicotinoyl)-3-((4-fluorophenyl) (methyl) amino) acrylate was synthesized by two steps including substitution and hydrolysis. The synthesis method was optimized, and structure was confirmed by H-1 NMR and MS spectrum. The synthesis method is optimized. The total yield of the two steps is 63.69%.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 149022-15-1, you can contact me at any time and look forward to more communication. Formula: C8H12ClN3OS.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem