Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 132-64-9, Name is Dibenzo[b,d]furan, molecular formula is C12H8O, belongs to naphthyridines compound. In a document, author is Akula, Mahesh, introduce the new discover, Recommanded Product: 132-64-9.
Synthesis and anti-tubercular activity of fused thieno-/furo-quinoline compounds
A simple route for preparation of 4-substituted thieno/furo[2,3-c]quinoline compounds is reported in this paper. These compounds were synthesized by using Suzuki coupling between appropriate boronic acid and 2-iodoaniline, followed by reaction with diverse aldehydes in the presence of a catalytic amount of FeCl3. Naphthyridine analogues were also prepared in order to demonstrate the efficacy of the developed method. Further anti-tubercular activity screening of the molecules was undertaken, wherein compounds bearing a fused furo[2,3-c][1,8]naphthyridine skeleton displayed highest activity. The best MIC (minimum inhibitory concentration) value of 5.6 mu mol was obtained for 4-(4-methoxyphenyl)furo[2,3-c][1,8]naphthyridine, which is found to be superior to the existing first line anti-tubercular drug ethambutol (7.6 mu mol).
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 132-64-9. Recommanded Product: 132-64-9.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem