Let¡¯s face it, organic chemistry can seem difficult to learn, Quality Control of Cyclohexanemethanol, Especially from a beginner¡¯s point of view. Like 100-49-2, Name is Cyclohexanemethanol, molecular formula is C8H14N4O7, belongs to imidazolidines compound. In a document, author is Boda, Sakram, introducing its new discovery.
A conventional and solid-state synthesis, biological activity, and molecular docking studies of 6-arylbenzo[4,5]imidazo[1,2-a] [1,8]naphthyridin-10-ols
An effective, practical, and simple approach toward the preparation of highly-substituted 6-arylbenzo[4, 5]imidazo[1,2-a][1,8]naphthyridin-10-ols 6(a-h) by the reaction of 3-aryl-1,8-naphthyridin-2-amines 3(a-h) with benzoquinone 4 in acid catalyzed cyclization under solid-state method, as well as conventional conditions, has been described. The products are obtained in good yields and in a solid of high purity. The major advantages of solid states are easy workup, low costs, short reaction time, good efficacy, and environment-friendly procedure. The newly synthesized compounds were thoroughly characterized using spectral data and elemental analyses. All compounds were screened for their biological evaluation. Predominantly 6b and 6c compounds showed the highest antibacterial activity. Moreover, all the synthesized compounds were docked against topoisomerase II DNA gyrase enzyme. [GRAPHICS]
If you are hungry for even more, make sure to check my other article about 100-49-2, Quality Control of Cyclohexanemethanol.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem