Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Product Details of 23814-12-2, 23814-12-2, Name is 1H-Benzo[d][1,2,3]triazole-5-carboxylic acid, SMILES is O=C(C1=CC=C(NN=N2)C2=C1)O, belongs to naphthyridines compound. In a document, author is Ramos, Eva, introduce the new discover.
Analysis of gene expression profiles of CR80, a neuroprotective 1,8-Naphthyridine
The 1,8-naphthyridine CR80 (ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b] [1,8] naphthyridine3- carboxylate) has shown interesting neuroprotective properties in in vitro and in vivo models of neurodegeneration. In spite of these promising outcomes, the molecular and cellular mechanisms underlying CR80 actions need to be further explored. Materials & methods: We herein report the signal transduction pathways involved in developmental, neuroprotective and stress-activated processes, as well as the gene expression regulation by CR80 in SH-SY5Y neuroblastoma cells. Results: The CR80 exposure upregulated several antioxidant enzymes (HO-1, GSR, SQSTM1, and TRXR1) and anti-apoptotic proteins (Bcl-xL, Bcl-2, P21, and Wnt6). Conclusion: The observed changes in gene expression would afford new insights on the neuroprotective profile of CR80.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 23814-12-2. Product Details of 23814-12-2.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem