Extracurricular laboratory: Discover of 132-64-9

If you are interested in 132-64-9, you can contact me at any time and look forward to more communication. SDS of cas: 132-64-9.

In an article, author is Wojcicka, Anna, once mentioned the application of 132-64-9, SDS of cas: 132-64-9, Name is Dibenzo[b,d]furan, molecular formula is C12H8O, molecular weight is 168.19, MDL number is MFCD00004968, category is naphthyridines. Now introduce a scientific discovery about this category.

SYNTHESIS AND IN VITRO ANTIPROLIFERATIVE SCREENING OF NEW 2,7-NAPHTHYRIDINE-3-CARBOXYLIC ACID HYDRAZIDE DERIVATIVES

The new pyrrolo[3,4-c]pyridines and 2,7-naphthyridine derivatives have been synthesized. 4-Hydroxy-8-methyl-l-oxo-6-phenyl-1,2-dihydro-2,7-naphthyridine-3-carboxylic acid hydrazide (4) was the key intermediate for the synthesis of the novel derivatives of various chemical structures: Schiff bases, 1,3,4-oxadiazoles, pyrazoles, carbohydrazides, semi- and thiosemicarbazides. The structures of these new compounds were confirmed by elemental analysis and IR, NMR and MS spectra. The antitumor activities of the obtained derivatives were examined. Eight of the twenty one newly synthesized compounds were qualified by the NCI (Bethesda, MD, USA) for in vitro screening against 60 different human tumor cell lines. The most active proved to be the Schiff bases.

If you are interested in 132-64-9, you can contact me at any time and look forward to more communication. SDS of cas: 132-64-9.

Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem