Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Formula: C7H5N3O2, 23814-12-2, Name is 1H-Benzo[d][1,2,3]triazole-5-carboxylic acid, SMILES is O=C(C1=CC=C(NN=N2)C2=C1)O, belongs to naphthyridines compound. In a document, author is Yagi, Yuki, introduce the new discover.
Expanding chemical space of DNA-binding molecules with three base-binding units
A new molecule NC3-3 designed to expand chemical space of parent molecule NCD by adding the third base-binding unit was reported. NC3-3 bound to the G-G mismatch in the 5′-CGG-3’/5′-CGG-3′ motif but not to that in 5′-GGC-3’/5′-GGC-3′. This binding selectivity is similar to that reported for NCD. Fluorimetric screening of NCD and NC3-3 to dsDNA library containing yGw/xGz motifs showed that NC3-3 still kept the sequence selectivity as we observed for NCD-binding. The third naphthyridine heterocycle in NC3-3 affected the mode of the binding, but a little effect on the sequence selectivity.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 23814-12-2. Formula: C7H5N3O2.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem