Chemical Research Letters, May 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. , HPLC of Formula: https://www.ambeed.com/products/91-76-9.html, 91-76-9, Name is 2,4-Diamino-6-phenyl-1,3,5-triazine, molecular formula is C9H9N5, belongs to naphthyridine compound. In a document, author is Pan, Jiafeng, introduce the new discover.
Routine detection of trace amounts of Pb2+ is of significant importance because it poses severe risks to human health and the environment. In this paper, a novel label-free fluorescence platform for the sensitive detection of Pb2+ has been successfully constructed by using Pb2+-specific 8-17 DNAzyme as the molecular recognition element, 2-amino-5,6,7-trimethyl-1,8-naphthyridine (ATMND) as the signal reporter, and exonuclease III (Exo III) as the signal amplifier. A good linearity between the fluorescence intensity and the logarithm of Pb2+ concentration was obtained in the range from 100 pM to 10 M with a correlation coefficient (R-2) of 0.99. The sensing system exhibited ultrasensitivity towards Pb2+ at low concentration (50 pM) without any labeling, modification, immobilization, or washing procedure. Besides, the proposed method was also highly selective for Pb2+ against other metal ions. This biosensor was robust and can be applied for the determination of Pb2+ in complex samples with desired recovery and good accuracy. With the successful demonstration of Pb2+ detection, the label-free biosensor can be readily expanded to monitor other targets in a simple, cost-effective, and ultrasensitive way by replacing the target-specific molecular recognition elements.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ¡®hit¡¯ molecules. I hope my blog about 91-76-9 is helpful to your research. HPLC of Formula: https://www.ambeed.com/products/91-76-9.html.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem