New research progress on 100-49-2 in 2021. 100-49-2, Name is Cyclohexanemethanol, molecular formula is C7H14O, Name: Cyclohexanemethanol, SMILES is OCC1CCCCC1 belongs to naphthyridine compound, is a common compound. In a patnet, author is Rounds, Heather R., once mentioned the new application about 100-49-2.
Dinuclear, strain-induced ring-opening reactions of vinylaziridines and vinylcyclopropanes are described. The previously reported [NDI]Ni-2(C6H6) complex (NDI = naphthyridine diimine) reacts with N-tosyl-2-vinylaziridine via C-N oxidative addition to generate a dinickel metallacyclic product. On the basis of this stoichiometric reactivity, the [NDI]Ni-2(C6H6) complex is shown to be a highly active catalyst for the rearrangement of vinylcyclopropane to cyclopentene. Notably, 2-phenyl-1-vinylcyclopropane undergoes regioselective activation at the less hindered C-C bond in contrast to the noncatalytic thermal rearrangement. DFT calculations provide insight into the ability of the Ni-Ni bond stabilize key intermediates and transition states along the catalytic pathway.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 100-49-2. Name: Cyclohexanemethanol.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem