Chemical Research Letters, May 2021. Chemistry is a science major with cience and engineering. The main research directions are chemical synthesis, and research on the structure and performance of functional materials. In an article, author is Ye, Pengqing, once mentioned the application of 2835-95-2, Name is 5-Amino-2-methylphenol. Now introduce a scientific discovery about this category, Quality Control of 5-Amino-2-methylphenol.
We report herein a rare-earth-metal-catalyzed insertion of a 2-pyridine C(sp(2))-H bond into an intramolecular unactivated vinyl bond. This reaction provides streamlined access to a range of azaindolines in moderate to excellent yields. The salient features of this reaction include simple and mild reaction conditions, 100% atom efficiency, and wide substrate scope. This methodology is also used to construct other nitrogen-containing compounds such as naphthyridine derivatives. A plausible mechanism for the formation of azaindolines involving initial C-H bond activation by the lanthanide complex followed by C=C insertion into a Ln-C bond to form an alkyl lanthanide species that subsequently undergoes cyclization is proposed.
Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. Welcome to check out more blogs about 2835-95-2, in my other articles. Quality Control of 5-Amino-2-methylphenol.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem