Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. 63503-60-6, Name is 3-Chlorophenylboronic acid, SMILES is ClC1=CC=CC(=C1)B(O)O, belongs to naphthyridine compound. In a document, author is Nam, TG, introduce the new discover, Computed Properties of https://www.ambeed.com/products/63503-60-6.html.
n-Alkyllithiums were added to alpha,alpha’-disubstituted-1,8-naphthyridines in non-polar solvents Such as Et2O-hexane mixtures. In polar solvents such as THF, alkyllithium acts as a base rather than a nucleophile. Regioselective addition was achieved for substrates capable of five-membered cyclic chelation of the (alkyl)lithium reagent. Substrates with a TBS-protected alcohol as the co-chelating moiety afforded the best combination of yield and regioselectivity. This methodology was Successfully employed in the preparation of two 6-amino-3-pyridinol analogs of pentamethyl-chromanol (PMC), an alpha-tocopherol derivative with its isoprenoid side chain truncated to a methyl group.
The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. In my other articles, you can also check out more blogs about 63503-60-6. Computed Properties of https://www.ambeed.com/products/63503-60-6.html.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem