The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5-Iodo-2-furaldehyde(SMILESS: IC1=CC=C(O1)C=O,cas:2689-65-8) is researched.Reference of 1,2-Bis(diphenylphosphino)ethane. The article 《Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells》 in relation to this compound, is published in ChemBioChem. Let’s take a look at the latest research on this compound (cas:2689-65-8).
Chem. inducers that can control target-protein localization in living cells are powerful tools to investigate dynamic biol. systems. We recently reported the retention using selective hook or “”RUSH”” system for reversible localization change of proteins of interest by addition/washout of small-mol. artificial ligands of streptavidin (ALiS). However, the utility of previously developed ALiS was restricted by limited solubility in water. Here, we overcame this problem by X-ray crystal structure-guided design of a more soluble ALiS derivative (ALiS-3), which retains sufficient streptavidin-binding affinity for use in the RUSH system. The ALiS-3-streptavidin interaction was characterized in detail. ALiS-3 is a convenient and effective tool for dynamic control of a-mannosidase II localization between ER and Golgi in living cells.
When you point to this article, it is believed that you are also very interested in this compound(2689-65-8)Product Details of 2689-65-8 and due to space limitations, I can only present the most important information.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem