Little discovery in the laboratory: a new route for 2689-65-8

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Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 2689-65-8, is researched, SMILESS is IC1=CC=C(O1)C=O, Molecular C5H3IO2Journal, Zhurnal Organicheskoi Khimii called Polar properties and reactivities of some 5-substituted furfurals, Author is Kogan, M. G.; Pustovarov, V. S.; Kolodyazhnyi, Yu. V.; Nazarova, Z. N.; Osipov, O.A., the main research direction is dipole moment furfurals; furfurals dipole moment; Hammett constant furfurals; reaction rates furfurals; rates reaction furfurals.Recommanded Product: 2689-65-8.

The dipole moments (μ) were determined of the following 5-substituted furfurals (I) (substituent and μ given): Et2N, 5.66; Me2N, 5.50; piperidino, 5.43; PhNMe, 4.95; morpholino, 4.81; Me, 3.94; CHO, 3.46; H, 3.57; Br, 3.37; Cl, 3.37; I, 3.29. Linear correlations were obtained between μ and Hammett σ constant of the substituents. The relative reaction rates (k) were also determined for the reactions of I with PhNH2. A linear plot was obtained when μ were plotted vs. log k. I (R = Me, NMe2, or NEt2) have in solution primarily the cis configuration.

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Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem