Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 2689-65-8, is researched, Molecular C5H3IO2, about Ligand-Promoted meta-C-H Functionalization of Benzylamines, the main research direction is ligand promoted meta CH functionalization benzylamine; amination; benzylamines; chlorination; meta-C−H arylation; pyridone ligand.Synthetic Route of C5H3IO2.
Meta-C-H functionalization of benzylamines has been developed using a PdII/transient mediator strategy. Using 2-pyridone ligands and 2-carbomethoxynorbornene (NBE-CO2Me) as the mediator, arylation, amination, and chlorination of benzylamines are realized. This protocol features a broad substrate scope and is compatible with heterocylic coupling partners. Moreover, the loading of the Pd can be lowered to 2.5 mol % by using the optimal ligand.
Compound(2689-65-8)Synthetic Route of C5H3IO2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-Iodo-2-furaldehyde), if you are interested, you can check out my other related articles.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem