The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-Iodo-2-furaldehyde( cas:2689-65-8 ) is researched.SDS of cas: 2689-65-8.Mocelo, R.; Pustovarov, V. published the article 《Study of the nucleophilic substitution of halogens in furan compounds. (I). Furfurals》 about this compound( cas:2689-65-8 ) in Revista sobre los Derivados de la Cana de Azucar. Keywords: halogenation furfural; halofurfural halogen exchange. Let’s learn more about this compound (cas:2689-65-8).
5-Bromofurfural (I, R = Br) was prepared by treating I (R = H) in dichloroethane with Br in the presence of hydroquinone. Reaction of I (R = Br) with LiCl in DMF gave 74% I (R = Cl) and with KI-HOAc gave 80% I (R = I). I (R = I) was similarly obtained in 44% yield from I (R = Cl). I (R = Cl) could also be converted to I (R = Br) with KBr-HOAc.
In addition to the literature in the link below, there is a lot of literature about this compound(5-Iodo-2-furaldehyde)SDS of cas: 2689-65-8, illustrating the importance and wide applicability of this compound(2689-65-8).
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem