The effect of reaction temperature change on equilibrium 2689-65-8

As far as I know, this compound(2689-65-8)COA of Formula: C5H3IO2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

COA of Formula: C5H3IO2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 5-Iodo-2-furaldehyde, is researched, Molecular C5H3IO2, CAS is 2689-65-8, about A new approach to furan-containing macrolactones. Author is Schmidt, Christoph Q.; Messmer, Ruth; Bracher, Franz; Krauss, Juergen.

Furan and THF heterocycles are part of many natural products, like the Galerucella pheromone, furano epothilones, bipinnatin, and amphidinolides. This paper describes a short and efficient synthetic approach to furan-containing macrolactones in 4 steps, including as key steps a Sonogashira reaction and an olefin metathesis. The resulting compounds were tested at the National Cancer Institute for their cytotoxicity, but did not exhibit significant cytotoxicity in the human tumor cell line screen.

As far as I know, this compound(2689-65-8)COA of Formula: C5H3IO2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem