The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-Iodo-2-furaldehyde( cas:2689-65-8 ) is researched.Electric Literature of C5H3IO2.Shen, Zhi-Liang; Lai, Yin-Chang; Wong, Colin Hong An; Goh, Kelvin Kau Kiat; Yang, Yong-Sheng; Cheong, Hao-Lun; Loh, Teck-Peng published the article 《Palladium-Catalyzed Cross-Coupling of Indium Homoenolate with Aryl Halide with Wide Functional Group Compatibility》 about this compound( cas:2689-65-8 ) in Organic Letters. Keywords: functional group tolerant indium homoenolate aryl halide coupling. Let’s learn more about this compound (cas:2689-65-8).
An efficient palladium-catalyzed cross-coupling of indium homoenolate with aryl halide is described. The reactions proceeded efficiently in DMA at 100 °C to afford the desired products of β-aryl ketones in moderate to good yields. Various important functional groups including ketone, ester, aldehyde, nitrile, hydroxide, and nitro groups can be well tolerated in the protocol.
In some applications, this compound(2689-65-8)Electric Literature of C5H3IO2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem