The influence of catalyst in reaction 91523-50-1

Compounds in my other articles are similar to this one(6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid)Safety of 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Safety of 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid, is researched, Molecular C10H11NO3, CAS is 91523-50-1, about Synthesis and murine antineoplastic activity of bis[carbamoyloxymethyl] derivatives of pyrrolo[2,1-a]isoquinoline. Author is Anderson, Wayne K.; McPherson, Howard L. Jr.; New, James S.; Rick, Arvela C..

The title compounds I (R = Me2CH, cyclohexyl, R1 = MeO; R = Me, Et, cyclohexyl, R1 = H) were prepared I (R1 = MeO) were prepared from m-(PhCH2O)C6H4CHO via phenolic cyclization of m-HOC6H4CH2CH2NH2 with glyoxylic acid to give the isoquinoline II, which underwent cyclization with MeO2CCCCO2Me to give the pyrroloisoquinoline III. All I had P 388 lymphocytic activity. I (R = Me2CH, R1 = MeO) was tested in an expanded tumor panel and was shown to be active against B16 melanocarcinoma, CD8F1 mammary, L1210 lymphoid leukemia, colon 38, and MX-1 human tumor breast xenograft systems.

Compounds in my other articles are similar to this one(6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid)Safety of 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem