Month: April 2022

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Bromo-1-(1-methyl-1H-pyrrol-2-yl)ethanone(SMILESS: CN1C(C(CBr)=O)=CC=C1,cas:65438-97-3) is researched.Application of 65438-97-3. The article 《4-Acetylamino-3-(imidazol-1-yl)-benzoic acids as novel inhibitors of influenza sialidase》 in relation to this compound, is published in European Journal of Medicinal Chemistry. Let’s take a look at the latest research on this compound (cas:65438-97-3).

Two methods for the synthesis of 4-acetylaminobenzoic acids substituted at the 3-position with imidazoles are described. Thus, 4-acetylamino-3-aminobenzoic acid tert-Bu ester was N-alkylated with RCH2COBr (R = Ph, Et, benzofuran-3-yl, etc.) followed by cyclization with cyanamide and hydrolysis to give imidazolylbenzoic acids I (R1 = Ph, furyl, Et, etc.; R2 = NH2). Imidazolylbenzoic acids I (R1 = H; R2 = NH2, H, Et) were prepared by addition of the appropriate imidazole to 3-fluoro-4-nitrobenzoic acid tert-Bu ester followed by reduction of the nitro group, acetylation, and hydrolysis. Many of the compounds are inhibitors of influenza virus sialidases with levels of activity similar to the recently described 4-acetylamino-3-guanidino-benzoic acid (BANA 113).

As far as I know, this compound(65438-97-3)Name: 2-Bromo-1-(1-methyl-1H-pyrrol-2-yl)ethanone can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Bromo-1-(1-methyl-1H-pyrrol-2-yl)ethanone, is researched, Molecular C7H8BrNO, CAS is 65438-97-3, about Electrochemical diselenylation of indolizines via intermolecular C-Se formation with 2-methylpyridines, α-bromoketones and diselenides.Application of 65438-97-3.

2-Methylpyridines, aryl bromomethyl ketones, and diselenides underwent electrochem. three-component cyclocondensation and selenylation reactions mediated by KI and K2CO3 in aqueous DMF to yield diselenylindolizines such as I [R = Ph, 4-R1C6H4, 3-R2C6H4, 2-FC6H4, 2,4-Cl2C6H3, 3,4-Cl2C6H3, 3,4-(MeO)2C6H3, 2-naphthyl, 1,3-benzodioxol-5-yl, 2-dibenzofuranyl, 1-methyl-2-pyrrolyl; R1 = Me, MeO, i-Bu, F, Cl, Br, I, F3C, Ph, PhCH2O, MeSO2; R2 = Me, MeO, Cl, Br].

As far as I know, this compound(65438-97-3)Application of 65438-97-3 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-Iodo-2-furaldehyde, is researched, Molecular C5H3IO2, CAS is 2689-65-8, about Photochemical reactivity of halofuran and halothiophene derivatives with benzimidazole, the main research direction is iodofuran benzimidazole photochem coupling; iodothiophene benzimidazole photochem coupling; benzimidazolylthiophene; benzimidazolylfuran; thiophene benzimidazolyl; furan benzimidazolyl.HPLC of Formula: 2689-65-8.

A photochem. approach to the synthesis of 5-(4-benzimidazolyl)-2-thiophenes, e.g., I (X = S, R = H, Me) and 5-(4-benzimidazolyl)-2-furan I (X = O, R = H) by the irradiation of benzimidazole with iodothiophenes II (X = S, R = H, Me) and iodofuran II (X = O, R = H) in MeCN is described.

As far as I know, this compound(2689-65-8)HPLC of Formula: 2689-65-8 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

Computed Properties of C9H8N2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 4-Methyl-1,8-naphthyridine, is researched, Molecular C9H8N2, CAS is 1569-17-1, about Nuclear magnetic resonance studies on σ-adducts of heterocyclic systems with nucleophiles. 18. Proton and carbon-13 nuclear magnetic resonance investigations on σ-adduct formation between 1,X-naphthyridines and some methyl-1,8-naphthyridines with potassium amide in liquid ammonia. Author is Van der Plas, H. C.; Van Veldhuizen, A.; Wozniak, M.; Smit, P..

The 1,5-, 1,6-, and 1,8-naphthyridines dissolved in liquid NH3 containing KNH2 showed the H-2 and C-2 resonance at about 4 and 90 ppm higher field, resp., than the H-2 and C-2 resonance of the naphthyridines observed in CDCl3 as NH2- added to all 3 naphthyridines at C-2 to give a 2-amino-1,2-dihydro-1,X-naphthyridinide ion. The 1,7-naphthyridine showed a more complex reactivity pattern toward NH2-. Besides addition at C-2, addition at C-6 and at C-8 is observed The relation of this study with that of the Chichibabin amination of the 1,X-naphthyridines is discussed. NH2- and 2-methyl- and 4-methyl-1,8-naphthyridine gave only deprotonation of the Me group; 3-methyl-1,8-naphthyridine and NH2- gave the 2-amino-1,2-dihydro-3-methyl-1,8-naphthyridinide ion.

As far as I know, this compound(1569-17-1)Computed Properties of C9H8N2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-Iodo-2-furaldehyde, is researched, Molecular C5H3IO2, CAS is 2689-65-8, about Direct synthesis of ester-containing indium homoenolate and its application in palladium-catalyzed cross-coupling with aryl halide, the main research direction is indium ester homoenolate preparation coupling aryl halide.COA of Formula: C5H3IO2.

An efficient method for the synthesis of ester-containing indium homoenolate via a direct insertion of indium into β-halo ester in the presence of CuI/LiCl is described. The synthetic utility of the indium homoenolate was demonstrated by palladium-catalyzed cross-coupling with aryl halides in DMA with wide functional group compatibility.

As far as I know, this compound(2689-65-8)COA of Formula: C5H3IO2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

Name: 5-Iodo-2-furaldehyde. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 5-Iodo-2-furaldehyde, is researched, Molecular C5H3IO2, CAS is 2689-65-8, about Synthesis and germistatic action of some 5-substituted 2-(α-furyl)-1,3-dioxanes. Author is Zelikman, Z. I.; Kul’nevich, V. G.; Shkrebets, A. I.; Pershin, G. N.; Mikerina, A. L..

Bactericidal furyldioxanes (I; R = H, Me, Br, iodo) were obtained in 71-82% yields by condensation of the appropriate furfural derivative with HOCH2C(NO2)-EtCH2OH. No activity was exhibited against Staphylococcus, Streptococcus, or tuberculosis bacteria, but I (R = H) was active against microspores, trichophytosis, and Achorion. I (R = Br, iodo) were also active against microspores and Achorion.

As far as I know, this compound(2689-65-8)Name: 5-Iodo-2-furaldehyde can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-Iodo-2-furaldehyde( cas:2689-65-8 ) is researched.Application of 2689-65-8.Chen, Yi-Hung; Knochel, Paul published the article 《Preparation of Aryl and heteroaryl indium(III) reagents by the direct insertion of indium in the presence of LiCl》 about this compound( cas:2689-65-8 ) in Angewandte Chemie, International Edition. Keywords: functionalized aryl heteroaryl indium halide preparation cross coupling iodoarene. Let’s learn more about this compound (cas:2689-65-8).

Sensitive functional groups, including ketone, aldehyde, and ester groups, may be present in aryl In reagents prepared in good to excellent yields by the treatment of aryl and heteroaryl iodides with In powder in the presence of LiCl. These functionalized organoindium(III) reagents readily undergo Pd-catalyzed cross-coupling with functionalized aryl iodides, including those containing NH or OH groups.

As far as I know, this compound(2689-65-8)Application of 2689-65-8 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Infrared spectroscopic study of the condensation reaction of halofurfural with ketones》. Authors are Usmanov, Z.; Tadzhieva, M. A..The article about the compound:5-Iodo-2-furaldehydecas:2689-65-8,SMILESS:IC1=CC=C(O1)C=O).COA of Formula: C5H3IO2. Through the article, more information about this compound (cas:2689-65-8) is conveyed.

The reactions of furfuryl iodide (I) and bromide (II) with ketones were investigated. NaOH (3-5 ml., 5%), 0.05 mole halofurfural, and 0.8-3 ml. ketone were added to 20 ml. solvent. The reaction lasted 1-2 hrs. The product was precipitated with 30-50 ml. H2O and dried. The light-yellow oily products were investigated in C2H4Cl2 solutions, the crystalline products in pressed KBr disks. The compositions of the condensation products of I with methyl nonyl ketone, methyl naphthyl ketone, and acetophenone were C16H23O2I, C17H11O2I, and C13H9O2I, resp. The condensations of II with methyl alkyl ketones, where the alkyl group was Et, Pr, Bu, amyl, hexyl, isopropyl, and isobutyl, and with acetophenone and acetylacetone, led to C9H9O2Br, C10H11O2Br, C11H13O2Br, C12H15O2Br, C13H17O2Br, C10H11O2Br, C11H13O2Br, C13H9O2Br, and C10H9O3Br, resp. The ir spectra indicate the functional groups present in the various products.

As far as I know, this compound(2689-65-8)COA of Formula: C5H3IO2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Halogen-substituted products of furfural, published in 1933, which mentions a compound: 2689-65-8, Name is 5-Iodo-2-furaldehyde, Molecular C5H3IO2, Synthetic Route of C5H3IO2.

Furfural diacetate (I) and Br in CHCl3 give 10% of sym-bromofurfural (2-bromo-5-formylfuran), b16 112°, m. 85°; PhNH2 in 50% AcOH gives a characteristic orange-red color; oxime, m. 101°; semicarbazone, m. 215° (corrected, decomposition); phenylhydrazone, m. 80-5°. The di-Et acetal and diacetate could not be prepared Concentrated EtOH-KOH gives bromopyromucic acid. Improved directions are given for the preparation of tetraiodofuran (67% yield). I in AcOH and Hg(OAc)2 give 82% of a trimercuriacetate compound, containing free Hg(OAc)2 which cannot be removed without decomposition of the Hg compound With 0.35% EtOH-HCl there results 86% of the trimercurichloride, which reacts with I in Et2O to give, among other products, sym-iodofurfural, m. 110°.

As far as I know, this compound(2689-65-8)Synthetic Route of C5H3IO2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem

COA of Formula: C5H3IO2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 5-Iodo-2-furaldehyde, is researched, Molecular C5H3IO2, CAS is 2689-65-8, about A new approach to furan-containing macrolactones. Author is Schmidt, Christoph Q.; Messmer, Ruth; Bracher, Franz; Krauss, Juergen.

Furan and THF heterocycles are part of many natural products, like the Galerucella pheromone, furano epothilones, bipinnatin, and amphidinolides. This paper describes a short and efficient synthetic approach to furan-containing macrolactones in 4 steps, including as key steps a Sonogashira reaction and an olefin metathesis. The resulting compounds were tested at the National Cancer Institute for their cytotoxicity, but did not exhibit significant cytotoxicity in the human tumor cell line screen.

As far as I know, this compound(2689-65-8)COA of Formula: C5H3IO2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem