Martin, Timothy J. published the artcileHigh Throughput Biodegradation-Screening Test To Prioritize and Evaluate Chemical Biodegradability, HPLC of Formula: 116-63-2, the publication is Environmental Science & Technology (2017), 51(12), 7236-7244, database is CAplus and MEDLINE.
Comprehensive assessment of environmental biodegradability of pollutants is limited by the use of low-throughput systems. These are epitomized by OECD Ready Biodegradability Tests (RBTs), where one sample from an environment may be used to assess a chem.’s ability to readily biodegrade or persist universally in that environment. This neglects the considerable inherent microbial variation spatially and temporally in any environment. Inaccurate designations of biodegradability or persistence can occur as a result. RBTs are central in assessing biodegradation fate of chems. and inferring exposure concentrations in environmental risk assessments. We developed a colorimetric assay for the reliable quantification of suitable aromatic compounds in a high throughput biodegradation screening test (HT-BST). The HT-BST accurately differentiated and prioritized a range of structurally diverse aromatic compounds based on their assigned relative biodegradabilities and Quant. Structure-Activity Relationship (QSAR) model outputs. Approx. 20,000 individual biodegradation tests were performed, returning analogous results to conventional RBTs. The effect of substituent group structure and position on biodegradation potential demonstrated a significant correlation (P<0.05) with Hammett’s constant for substituents on position 3 of the phenol ring. The HT-BST may facilitate the rapid screening of 100,000 chems. reportedly manufactured in Europe and reduce the need for higher-tier fate and effects tests.
Environmental Science & Technology published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, HPLC of Formula: 116-63-2.
Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem