New Advances in Chemical Research in 2021. Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 39156-41-7, Name is 4-Methoxybenzene-1,3-diamine sulfate, molecular formula is , belongs to naphthyridine compound. In a document, author is Sun, Jianfei, Product Details of 39156-41-7.
Response surface methodology was designed to optimize the process parameters for the preparation of the tosufloxacin tosylate/hydroxypropyl-beta-cyclodextrin inclusion complex by supercritical antisolvent method (SAS). The optimum inclusion conditions were temperature 45 degrees C, pressure 12 MPa, molar ratio 1:1, and mixed solvent 20% DCM, in which case the inclusion efficiency was 15.18%. Three-dimensional response plots revealed that molar ratios and mixed solvents have a more pronounced effect on inclusion efficiency than temperature and pressure. Characterization results of SEM, EDX, PXRD and FT-IR confirmed that the inclusion complex was successfully prepared, and the inclusion sites of all inclusion complexes were located on the phenyl ring A, pyrrolidine and naphthyridine ring protons. The dissolution of the inclusion complex in the pH 6.8 buffer solution was up to 68.14%, indicating that the inclusion complex prepared by the SAS process could significantly improve the dissolution of tosufloxacin tosylate. (C) 2019 Elsevier B.V. All rights reserved.
These may comprise an expansion of the substrate scope from aromatic and heteroaromatic compounds to other hydrocarbons. If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 39156-41-7, Product Details of 39156-41-7.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem