New discoveries in chemical research and development in 2021. 91-76-9, Name is 2,4-Diamino-6-phenyl-1,3,5-triazine, molecular formula is C9H9N5, Safety of 2,4-Diamino-6-phenyl-1,3,5-triazine, belongs to naphthyridine compound, is a common compound. In a patnet, author is Ma, Wenpeng, once mentioned the new application about 91-76-9.
The first asymmetric hydrogenation of 2,7-disubstituted 1,3-naphthyridines catalyzed by chiral cationic ruthenium diamine complexes has been developed. A wide range of U-naphthyridine derivatives were effectively hydro-genated to give 1,2,3,4-tetrahydro-1,8-naphthyridines with up to 99% ee and full conversions. The method provides a practical and facile approach to the preparation of valuable chiral heterocyclic building blocks and useful motifs for a new kind of P,N-ligand.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. In my other articles, you can also check out more blogs about 91-76-9. Safety of 2,4-Diamino-6-phenyl-1,3,5-triazine.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem