New Advances in Chemical Research in 2021. In an article, author is Kumar, Vivek, once mentioned the application of 99-09-2, Name is 3-Nitroaniline, molecular formula is C6H6N2O2, molecular weight is 138.124, category is naphthyridine. Now introduce a scientific discovery about this category, Recommanded Product: 99-09-2.
A number of 1,8-naphthyridine derivatives (22-62) have been synthesized and screened for their in vitro cytotoxicity against eight tumors and two non-tumor cell lines. Halogen substituted 1,8-naphthyridine-3-caboxamide derivatives showed potent activity with compound 47 having IC(50) of 0.41 and 0.77 mu M on MIAPaCa and K-562 cancer cell lines, respectively while, compound 36 had IC(50) of 1.19 mu M on PA-1 cancer cell line. However, one of the unsubstituted 1,8-naphthyridine-C-3′-heteroaryl derivative 29 showed potent cytotoxicity with IC(50) of 0.41 and 1.4 mu M on PA-1 and SW620 cancer cell lines, respectively. These compounds were also evaluated for anti-inflammatory activity as suggested by downregulation of proinflammaotory cytokines.
Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. Welcome to check out more blogs about 99-09-2, in my other articles. Recommanded Product: 99-09-2.
Reference:
1,8-Naphthyridine – Wikipedia,
,1,8-Naphthyridine | C8H6N2 – PubChem