In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Formation of α-chiral centers by asymmetric β-C(sp3)-H arylation, alkenylation, and alkynylation, published in 2017-02-03, which mentions a compound: 2689-65-8, mainly applied to enantioselective arylation alkenylation alkynylation isobutyric acid amide organic iodide, Recommanded Product: 5-Iodo-2-furaldehyde.
The enzymic β-C-H hydroxylation of the feedstock chem. isobutyric acid has enabled the asym. synthesis of a wide variety of polyketides. The analogous transition metal-catalyzed enantioselective β-C-H functionalization of isobutyric acid-derived substrates should provide a versatile method for constructing useful building blocks with enantioenriched α-chiral centers from this abundant C-4 skeleton. However, the desymmetrization of ubiquitous iso-Pr moieties by organometallic catalysts has remained an unanswered challenge. Herein, the authors report the design of chiral mono-protected aminomethyl oxazoline ligands that enable desymmetrization of iso-Pr groups via palladium insertion into the C(sp3)-H bonds of one of the prochiral Me groups. We detail the enantioselective β-arylation, -alkenylation, and -alkynylation of isobutyric acid/2-aminoisobutyric acid derivatives, which may serve as a platform for the construction of α-chiral centers.
From this literature《Formation of α-chiral centers by asymmetric β-C(sp3)-H arylation, alkenylation, and alkynylation》,we know some information about this compound(2689-65-8)Recommanded Product: 5-Iodo-2-furaldehyde, but this is not all information, there are many literatures related to this compound(2689-65-8).
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem