Erkin, A. V.; Krutikov, V. I. published the article 《4-arylamino-2-(2-acetoxyethyl)amino-6-methylpyrimidines: Synthesis, deacetylation, and biological activity》. Keywords: ethanolamine acetate arylaminopyrimidinyl tuberculostatic preparation; pyrimidinediamine acetoxyethyl aryl tuberculostatic preparation; deacetylation acetoxyethylaminopyrimidine.They researched the compound: 4-Methyl-6-(methylthio)pyrimidin-2-ol( cas:16710-11-5 ).Application of 16710-11-5. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:16710-11-5) here.
The reaction of 2-(2-acetoxyethyl)amino-4-chloro-6-methylpyrimidine with aromatic amines leads to a series of 4-arylamino-2-(2-acetoxyethyl)amino-6-methylpyrimidines. Deacetylation of these compounds proceeds in both acidic and basic media. Most of the (arylamino)pyrimidines obtained exhibit a pronounced antituberculous effect.
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Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem