In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Iterative Arylation of Amino Acids and Aliphatic Amines via δ-C(sp3)-H Activation: Experimental and Computational Exploration, published in 2019, which mentions a compound: 2689-65-8, mainly applied to arylalkyl amine preparation; aliphatic amine aryl iodide arylation palladium catalyst; amino acid derivative aryl iodide arylation palladium catalyst; BODIPY labeling; arylation; density functional calculations; mechanistic studies; natural products, Reference of 5-Iodo-2-furaldehyde.
Directed C-H functionalization has been realized as a complementary tool to the traditional approaches for a straightforward access of non-proteinogenic amino acids; albeit such a process is restricted mostly up to the γ-position. In the present work, we demonstrate the diverse (hetero)arylation of amino acids and analogous aliphatic amines selectively at the remote δ-position by tuning the reactivity controlled by ligands. An organopalladium δ-C(sp3)-H activated intermediate has been isolated and crystallog. characterized. Mechanistic investigations carried out exptl. in conjunction with computational studies shed light on the difference in the mechanistic picture depending on the substrate structure.
Here is just a brief introduction to this compound(2689-65-8)Reference of 5-Iodo-2-furaldehyde, more information about the compound(5-Iodo-2-furaldehyde) is in the article, you can click the link below.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem