The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-Iodo-2-furaldehyde( cas:2689-65-8 ) is researched.Application of 2689-65-8.Chen, Yi-Hung; Knochel, Paul published the article 《Preparation of Aryl and heteroaryl indium(III) reagents by the direct insertion of indium in the presence of LiCl》 about this compound( cas:2689-65-8 ) in Angewandte Chemie, International Edition. Keywords: functionalized aryl heteroaryl indium halide preparation cross coupling iodoarene. Let’s learn more about this compound (cas:2689-65-8).
Sensitive functional groups, including ketone, aldehyde, and ester groups, may be present in aryl In reagents prepared in good to excellent yields by the treatment of aryl and heteroaryl iodides with In powder in the presence of LiCl. These functionalized organoindium(III) reagents readily undergo Pd-catalyzed cross-coupling with functionalized aryl iodides, including those containing NH or OH groups.
As far as I know, this compound(2689-65-8)Application of 2689-65-8 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem