Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Organic Letters called Stereospecific Synthesis of Tri- and Tetrasubstituted α-Fluoroacrylates by Mizoroki-Heck Reaction, Author is Rousee, Kevin; Bouillon, Jean-Philippe; Couve-Bonnaire, Samuel; Pannecoucke, Xavier, which mentions a compound: 2689-65-8, SMILESS is IC1=CC=C(O1)C=O, Molecular C5H3IO2, SDS of cas: 2689-65-8.
Ligand-free, efficient, palladium-catalyzed Mizoroki-Heck reaction between Me α-fluoroacrylate and arene or hetarene iodides is reported for the first time. The reaction is stereospecific and provides fair to quant. yields of fluoroalkenes. The Mizoroki-Heck reaction starting from more hindered and usually reluctant trisubstituted acrylate, to access tetrasubstituted fluoroalkenes, is also reported. Finally, the use of a three-step synthesis sequence, including Mizoroki-Heck reaction, allows the synthesis of fluorinated analogs of therapeutic agents with high yield.
Although many compounds look similar to this compound(2689-65-8)SDS of cas: 2689-65-8, numerous studies have shown that this compound(SMILES:IC1=CC=C(O1)C=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
1,8-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N2 – PubChem