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The electric dipole moments of 1,8-naphthyridine, 1-8-diazabiphenylene, and pyrido left bracket 3,2-g right bracket quinoline have been determined experimentally. The measured values in benzene are 4. 10, 4. 23, and 4. 02 D, respectively. The larger value for 2 is attributed to its distorted molecular geometry.

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Reference£º
1,192-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N186 – PubChem

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Naphthyridines of the formula I STR1 where R1 is an unsubstituted or substituted phenyl ring or heteroaromatic radical and R2 -R6 are hydrogen, alkyl, alkenyl, cycloalkyl, haloalkyl, alkoxyalkyl, aminoalkyl, unsubstituted or substituted phenyl, benzyl, unsubstituted or substituted heteroaryl linked via a carbon, cyano, nitro, carboxyl, sulfonylmethyl, alkoxycarbonyl, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, alkanoyl, benzoyl, it being possible for R4 and R5 or R5 and R6 to be bonded by a methylene chain or by a CH=CH–CH=CH group.

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Reference£º
1,20-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N14 – PubChem

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254-60-4, Name is 1,8-Diazanaphthalene, belongs to naphthyridine compound, is a common compound. Application In Synthesis of 1,8-DiazanaphthaleneIn an article, once mentioned the new application about 254-60-4.

Metal- and solvent-free reaction of quinolines with two molecules of aryltrifluoroacetylacetylenes afforded 3-arylethynyl-3-trifluoromethyl-1,3-oxazinoquinolines in up to 92% yields. The formation of a zwitterionic intermediate in the first step triggered a multistep domino reaction. This one-pot synthesis opens an easy access to novel quinoline derivatives bearing trifluoromethyl, acetylene and ketone functions, thus providing a powerful tool for drug design.

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1,57-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N51 – PubChem

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To improve the strength and maintain the inherent properties of flame-retardant polyacrylonitrile (FR-PAN) fiber, a commercialized hydrocarbon polymer, i.e., poly (vinyl alcohol) (PVA), used as an enhancement component, was blended with polyacrylonitrile (PAN) spinning dope to fabricate a PVA/PAN composite fiber through wet-spun technology. Then, cross-linked PVA/PAN composite fiber (C-PVA/PAN) was acquired via boric acid cross-linking. Finally, flameretardant C-PVA/PAN fiber (FR-PVA/PAN) was prepared by phosphorylation. The structures of the samples were characterized by Fourier transform infrared analysis (FTIR) and X-ray photoelectron spectroscopy (XPS). The thermogravimetric analysis (TGA) results reveal that the thermal stability of the composite fiber is lower than that of the pristine PAN fiber. However, the char residue of the composite fiber is higher than that of the control sample, wherein, FR-PVA/PAN has the highest char residue of 62.5 wt% at 800 C. The results regarding the combustion properties of FR-PVA/PAN show that the fire hazard of FR-PVA/PAN is restrained greatly, indicating excellent flame-retardant performance. The corresponding flame-retardant mechanism of FR-PAV/PAN is investigated by Pyrolysis gas chromatography and mass spectrometry (Py-GC/MS) and thermogravimetric analysis coupled with Fourier transform infrared analysis (TG-FTIR). The results indicate the gas-phase and condensed-phase flame-retardant mechanisms.

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1,240-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N234 – PubChem

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Reference of 254-60-4, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 254-60-4, molcular formula is C8H6N2, introducing its new discovery.

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Naphthyridine and related derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.

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1,31-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N25 – PubChem

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Background: A set of antibiotic fluoroquinolones with confirmed antimicrobial activity were analyzed with the use of two types of quantum chemical calculation methods and quantitative structure-activity relationships (QSAR). Objective: The purpose of this study was to demonstrate the common and differentiating characteristics of the above-mentioned chemical compounds alike physicochemically as well as pharmacologically based on the quantum chemical calculations and microbiological activity data. Methods: During the study PCA and MLR analysis were performed, as the types of proposed chemometric approach. The semi-empirical level of in silico molecular modeling was performed for calculations of molecular descriptors. Results: QSAR models were proposed based on chosen descriptors. The relationship between the structure and microbiological activity and physicochemical parameters data was able to class and describe them with the use of statistically significant molecular descriptors. Conclusion: The applied chemometric approaches revealed the influential features of tested structures responsible for the antimicrobial activity of analyzed compounds.

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1,157-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N151 – PubChem

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Supramolecular block copolymers comprising isotactic polypropylene (iPP) and ethylene-propylene random copolymers (EP) with complementary quadruple hydrogen bonding junctions have been prepared by melt-mixing of iPP having a 2-ureido-4[1H]-pyrimidinone (UPy) group (iPP-UPy) and elastic EP bearing a 2,7-diamido-1,8-naphthyridine (Napy) group (EP-Napy). Transmission electron microscope (TEM) analysis of the iPP-UPy/EP-Napy composite showed that the elastic EP domains were well dispersed in the iPP matrix compared with the traditional iPP/EP impact polypropylene copolymer (IPC). The iPP-UPy/EP-Napy hydrogen-bonded pseudo block copolymer effectively acts as a compatibilizer in the IPC and contributes to improved mechanical properties of the resulting iPP/EP composite. There is good correlation between impact strength of the IPC and EP domain size observed by the TEM analysis. The use of the complementary quadruple hydrogen bonding system for blending two immiscible polymers has been shown to result in smaller domain sizes of the EP-phase in the iPP and consequently improved mechanical properties of the supramolecular iPP/EP blends.

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Reference£º
1,209-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N203 – PubChem

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Because of the peculiar dynamic covalent reactivity of boronic acids to form tetraboronate derivatives, interest in using their aryl derivatives in materials science and supramolecular chemistry has risen. Nevertheless, their ability to form H-bonded complexes has been only marginally touched. Herein we report the first solution and solid-state binding studies of the first double-H-bonded DD¡¤AA-type complexes of a series of aromatic boronic acids that adopt a syn-syn conformation with suitable complementary H-bonding acceptor partners. The first determination of the association constant (Ka) of ortho-substituted boronic acids in solution showed that Ka for 1:1 association is in the range between 300 and 6900 M-1. Crystallization of dimeric 1:1 and trimeric 1:2 and 2:1 complexes enabled an in-depth examination of these complexes in the solid state, proving the selection of the -B(OH)2 syn-syn conformer through a pair of frontal H-bonds with the relevant AA partner. Non-ortho-substituted boronic acids result in “flat” complexes. On the other hand, sterically demanding analogues bearing ortho substituents strive to retain their recognition properties by rotation of the ArB(OH)2 moiety, forming “T-shaped” complexes. Solid-state studies of a diboronic acid and a tetraazanaphthacene provided for the first time the formation of a supramolecular H-bonded polymeric ribbon. On the basis of the conformational dynamicity of the -B(OH)2 functional group, it is expected that these findings will also open new possibilities in metal-free catalysis or organic crystal engineering, where double-H-bonding donor boronic acids could act as suitable organocatalysts or templates for the development of functional materials with tailored organizational properties.

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Reference£º
1,117-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N111 – PubChem

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Due to the difficulty in achieving high efficiency and high color purity simultaneously, blue emission is the limiting factor for the performance and stability of OLEDs. Since 2003, we have been working on organic light-emitting diodes (OLEDs), especially on blue light. After a series of molecular designs, novel strategies have been proposed from different aspects. At first, highly efficient deep blue emission could be achieved through molecular design with highly twisted structure to suppress fluorescence quenching and redshift. Deep blue emitters with high efficiency in solid state, a twisted structure with aggregation induced emission (AIE) characteristics was incorporated to inhibit molecular aggregation, and triplet-triplet fusion (TTF) and hybridized localized charge transfer (HLCT) were adopted to increase the ratio of triplet exciton used. Secondly, a highly efficient blue OLED could be achieved through improving charge transport. New electron transport materials (ETMs) with wide band gap were developed to control charge transport balance in devices. Thirdly, a highly efficient deep blue emission could be achieved through a mesoscopic structure of out-coupling layer. A mesoscopic photonic structured organic thin film was fabricated on the top of metal electrode by self-aggregation in order to improve the light out-coupling efficiency.

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1,65-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N59 – PubChem

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The reaction of indole (2-methylindole) with 1,5-, 1,6-, and 1,8-naphthyridines at 20 deg C, in the presence of benzoyl chloride, leads to the preferential formation of dihydro structures with one indolyl substituent at the alpha-position to the hetero atom.With increase in temperature, dibenzoyl and monobenzoyl tetrahydro-substituted naphthyridines with two indolyl residues in both pyridine ring are formed besides the above compounds.

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Reference£º
1,253-Naphthyridine – Wikipedia,
1,8-Naphthyridine | C8H6N247 – PubChem