Category: 2960-93-2

Svejstrup, Thomas D. published the artcileSynthesis of Arylamines via Aminium Radicals, Name: 2,2′-Dimethoxy-1,1′-binaphthalene, the publication is Angewandte Chemie, International Edition (2017), 56(47), 14948-14952, database is CAplus and MEDLINE.

Arylamines constitute the core structure of many therapeutic agents, agrochems., and organic materials. The development of methods for the efficient and selective construction of these structural motifs from simple building blocks is desirable but still challenging. We demonstrate that protonated electron-poor O-aryl hydroxylamines give aminium radicals in the presence of Ru(bpy)₃Cl₂. These highly electrophilic species undergo polarized radical addition to aromatic compounds in high yield and selectivity. We successfully applied this method to the late-stage modification of chiral catalyst templates, therapeutic agents, and natural products.

Angewandte Chemie, International Edition published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C13H10O3, Name: 2,2′-Dimethoxy-1,1′-binaphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Roy, Biswajit published the artcileGround-State Proton-Transfer (GSPT)-Assisted Enhanced Two-Photon Uncaging from a Binol-based AIE-Fluorogenic Phototrigger, Application of 2,2′-Dimethoxy-1,1′-binaphthalene, the publication is Organic Letters (2021), 23(6), 2308-2313, database is CAplus and MEDLINE.

We demonstrated for the first time without any chem. modification the two-photon absorption (TPA) cross-section can be enhanced and red-shifted to the near-IR (NIR) region by the ground-state proton-transfer (GSPT) process. Using GSPT, we developed a simple binol-based aggregation-induced emission (AIE)-fluorogenic phototrigger having a large two-photon uncaging cross-section in the “phototherapeutic window”. As a proof of concept, we showed our phototrigger for the release of two different anticancer drugs in the NIR region.

Organic Letters published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Application of 2,2′-Dimethoxy-1,1′-binaphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Woods, Ross M. published the artcileEnantiomeric separation of biaryl atropisomers using cyclofructan based chiral stationary phases, Name: 2,2′-Dimethoxy-1,1′-binaphthalene, the publication is Journal of Chromatography A (2014), 172-181, database is CAplus and MEDLINE.

Normal phase chiral HPLC methods are presented for the enantiomeric separation of 30 biaryl atropisomers including 18 new compounds recently produced via a novel synthetic approach. Three new cyclofructan based chiral stationary phases were evaluated. Separations were achieved for all but six analytes and the LARIHC CF6-P alone provided 15 baseline separations Effects of polar modifiers and temperature effects also were studied. Apparent thermodn. parameters were determined by van’t Hoff plots. Preparative scale methods were developed and employed resulting in the 1st ever isolation of these novel atropisomers in their pure enantiomeric form. Insights into the mechanism of retention and chiral discrimination are presented.

Journal of Chromatography A published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C6H13N3O2, Name: 2,2′-Dimethoxy-1,1′-binaphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Wood, Natasha C. L. published the artcileMediated electron transfer from lithium investigated voltammetrically in tetrahydrofuran: why are some mediators more effective reducing reagents than others?, SDS of cas: 2960-93-2, the publication is Journal of Physical Organic Chemistry (2007), 20(10), 732-742, database is CAplus.

A study of a range of aromatic mols. was studied electrochem. to determine what makes an effective reducing mediator. With the aim of developing a better understanding of electron transfers (ETs) mediated from Li in functional group reduction, single ET reactions are reported. Typical reaction conditions involved the use of aromatic mediators such as naphthalene, anthracene, 4,4′-di-tert-butyl-1,1′-biphenyl (DBB) with Li metal in THF at -78°. The results of these experiments showed that some mediators were more effective reducing reagents than others. Cryoelectrochem. procedures are used to mimic the conditions of the SET (single electron transfer) reactions to study the exact nature and role of the mediator formed upon ET. Electrogenerated and stabilized radical anions of anthracene at -78° mediate the reduction of organic substrates, whereas the more reactive dianion is quickly protonated and therefore unable to act as an ET reagent; direct electrochem. reduction of the sulfide, Ph 3-phenylpropyl sulfide (RSPh) gives the thiol, thiophenol, and propylbenzene whereas mediated reduction gives the dimer, di-Ph disulfide and Pr benzene. The possibility to selectively reduce a substrate with either a single electron or with 2 electrons is possible by using either the radical anion (mediated) or via the direct electroreduction DBB and naphthalene (both single electron accepting species only) are the most effective reducing reagents. Anthracene and other 2-electron accepting species only showed effective reducing ability when a stoichiometric amount of Li was used therefore preventing the over-reduction to the dianion.

Journal of Physical Organic Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C18H21BO4, SDS of cas: 2960-93-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Sancho, Raquel published the artcileA (4R)-hydroxy-L-proline-derived chiral scaffold and its oligomers as chiral selectors in liquid chromatography chiral stationary phases for enantioseparation, Related Products of naphthyridine, the publication is Journal of Separation Science (2006), 29(6), 905-914, database is CAplus and MEDLINE.

The chromatog. behavior of a poly-L-proline-derivatized chiral stationary phase (CSP) is compared to the corresponding single proline-derived CSP. Structurally diverse racemic test compounds and mobile phases, including normal- and RP conditions, were used. Although the application domain of the poly-L-proline-derived CSP (CSP-3) was considerably restricted, this CSP showed a higher retention and a slightly broader application domain than the monomeric analog (CSP-1) when heptane/2-PrOH was used as mobile phase. The presence of an alc. in the mobile phase was essential for enantioseparation in the poly-L-proline-derived CSP when normal-phase conditions were applied.

Journal of Separation Science published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Fang, Jingxian published the artcileGraphene-Oxide-Promoted Direct Dehydrogenative Coupling Reaction of Aromatics, HPLC of Formula: 2960-93-2, the publication is Asian Journal of Organic Chemistry (2018), 7(2), 355-358, database is CAplus.

Graphene oxide, which is a popular 2D carbon material, promoted a direct dehydrogenative coupling reaction of aromatics Homo-coupling and cross-coupling reactions were achieved in good yields in the presence of graphene oxide. This strategy was simple and did not required any other additives, such as acid/base or ligand. The reaction was easily scaled up to gram level.

Asian Journal of Organic Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, HPLC of Formula: 2960-93-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Mosquera, Angeles published the artcileSynthesis of Axially Chiral 1,1′-Binaphthalenes by Palladium-Catalysed Cross-Coupling Reactions of Triorganoindium Reagents, Recommanded Product: 2,2′-Dimethoxy-1,1′-binaphthalene, the publication is European Journal of Organic Chemistry (2013), 2013(13), 2555-2562, database is CAplus.

1,1′-Binaphthalenes and heterocyclic analogs can be efficiently prepared by palladium-catalyzed cross-coupling reactions between tri(1-naphthyl)indium reagents and 1-halonaphthalenes and haloisoquinolines. The reactions were usually carried out in THF at 80° with a slight excess of the indium reagent (40 mol-%) and a low catalyst loading (4 mol-% Pd) to afford the cross-coupling products in good yields (45-99 %). The method allows the synthesis of sterically hindered 2-substituted and 2,2′-disubstituted 1,1′-binaphthalenes and naphthylisoquinolines. In addition, the coupling reactions can be performed enantioselectively and the best enantiomeric excesses were obtained by using the chiral amino-phosphane ferrocenyl ligand (R,S)-PPFA.

European Journal of Organic Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Recommanded Product: 2,2′-Dimethoxy-1,1′-binaphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Woods, Ross M. published the artcileEnantiomeric separation of biaryl atropisomers using cyclofructan based chiral stationary phases, Name: 2,2′-Dimethoxy-1,1′-binaphthalene, the publication is Journal of Chromatography A (2014), 172-181, database is CAplus and MEDLINE.

Normal phase chiral HPLC methods are presented for the enantiomeric separation of 30 biaryl atropisomers including 18 new compounds recently produced via a novel synthetic approach. Three new cyclofructan based chiral stationary phases were evaluated. Separations were achieved for all but six analytes and the LARIHC CF6-P alone provided 15 baseline separations Effects of polar modifiers and temperature effects also were studied. Apparent thermodn. parameters were determined by van’t Hoff plots. Preparative scale methods were developed and employed resulting in the 1st ever isolation of these novel atropisomers in their pure enantiomeric form. Insights into the mechanism of retention and chiral discrimination are presented.

Journal of Chromatography A published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C6H13N3O2, Name: 2,2′-Dimethoxy-1,1′-binaphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Wood, Natasha C. L. published the artcileMediated electron transfer from lithium investigated voltammetrically in tetrahydrofuran: why are some mediators more effective reducing reagents than others?, SDS of cas: 2960-93-2, the publication is Journal of Physical Organic Chemistry (2007), 20(10), 732-742, database is CAplus.

A study of a range of aromatic mols. was studied electrochem. to determine what makes an effective reducing mediator. With the aim of developing a better understanding of electron transfers (ETs) mediated from Li in functional group reduction, single ET reactions are reported. Typical reaction conditions involved the use of aromatic mediators such as naphthalene, anthracene, 4,4′-di-tert-butyl-1,1′-biphenyl (DBB) with Li metal in THF at -78°. The results of these experiments showed that some mediators were more effective reducing reagents than others. Cryoelectrochem. procedures are used to mimic the conditions of the SET (single electron transfer) reactions to study the exact nature and role of the mediator formed upon ET. Electrogenerated and stabilized radical anions of anthracene at -78° mediate the reduction of organic substrates, whereas the more reactive dianion is quickly protonated and therefore unable to act as an ET reagent; direct electrochem. reduction of the sulfide, Ph 3-phenylpropyl sulfide (RSPh) gives the thiol, thiophenol, and propylbenzene whereas mediated reduction gives the dimer, di-Ph disulfide and Pr benzene. The possibility to selectively reduce a substrate with either a single electron or with 2 electrons is possible by using either the radical anion (mediated) or via the direct electroreduction DBB and naphthalene (both single electron accepting species only) are the most effective reducing reagents. Anthracene and other 2-electron accepting species only showed effective reducing ability when a stoichiometric amount of Li was used therefore preventing the over-reduction to the dianion.

Journal of Physical Organic Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C18H21BO4, SDS of cas: 2960-93-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Liu, Kun Ming published the artcileIron catalyzed oxidative assembly of N-heteroaryl and aryl metal reagents using oxygen as an oxidant, COA of Formula: C22H18O2, the publication is Chemical Communications (Cambridge, United Kingdom) (2015), 51(6), 1124-1127, database is CAplus and MEDLINE.

An equivalent amount of N-heteroaryl and aryl Grignard or lithium reagents, after mediation by an equivalent of titanate, was facilely coupled to furnish N-heteroaryl-aryl compounds under the catalysis of FeCl₃/TMEDA at ambient temperature using oxygen as an oxidant. Most of the common N-heteroaryls were all good candidates, and thus provided a general, green and practical protocol for the flexible construction of various N-heteroaryl-aryl structures.

Chemical Communications (Cambridge, United Kingdom) published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, COA of Formula: C22H18O2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem