Category: naphthyridine

Luo, Lin published the artcileStudy on molybdenum blue spectrophotomertric method for determination of trace silicon in high purity hafnium, Recommanded Product: 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, the publication is Henan Huagong (2015), 32(5), 60-62, database is CAplus.

The research develops a molybdenum blue spectrophotometry in high-purity hafnium trace silicon, using hydrofluoric acid to dissolve the sample, adding boric acid masking fluoride ion. adding ammonium molybdate to react with silicic acid ions formed by the yellow silicon phase heteropolyacid complexes with tartaric acid medium at 1-amino-2-naphthol-4-sulfonic acid, measuring the absorbance and recovery tests. The test results showed that: the method is simple, qual. method, reproducibility, good accuracy, to meet the trace anal. inspection visit silicon requirements.

Henan Huagong published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Recommanded Product: 4-Amino-3-hydroxynaphthalene-1-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Pan, Wenjing published the artcileA mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh₂ and ^tBuOK, Category: naphthyridine, the publication is Organic & Biomolecular Chemistry (2021), 19(35), 7633-7640, database is CAplus and MEDLINE.

A general method for the demethylation, debenzylation, and deallylation of aryl ethers ROMe (R = C₆H₅, 3-FC₆H₄, 2-naphthyl, etc.), R¹OCH²Ph (R¹ = C₆H₅, 5,6,7,8-tetrahydronaphthalen-2-yl, 2-naphthyl, etc.) and R²OCH²CH=CH² (R² = C₆H₅, 2,3-dimethylphenyl, 1-naphthyl, etc.) using HPPh₂ and ^tBuOK is reported. The reaction features mild and metal-free reaction conditions, broad substrate scope, good functional group compatibility, and high chem. selectivity towards aryl ethers over aliphatic structures. Notably, this approach is competent to selectively deprotect the allyl or benzyl group, making it a general and practical method in organic synthesis.

Organic & Biomolecular Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Category: naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zhao, Qing published the artcileAn Efficient Method for Sterically Demanding Suzuki-Miyaura Coupling Reactions, Product Details of C22H18O2, the publication is Chemistry – A European Journal (2013), 19(7), 2261-2265, database is CAplus and MEDLINE.

The synthesis of tetra-ortho-substituted biaryls bearing secondary alkyl ortho substituents, such as iso-Pr groups, through Suzuki-Miyaura couplings was catalyzed by Pd(OAc)₂ and a biaryl monophosphorus ligand, e.g. I. E.g., in presence of Pd(OAc)₂, I, and NaOtBu, Suzuki-Miyaura coupling of 2-bromo-1,3-dimethoxybenzene and 2,4,6-triisopropylphenylboronic acid gave 97% tetra-ortho-substituted biaryl (II).

Chemistry – A European Journal published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C18H34N4O5S, Product Details of C22H18O2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zou, Zhenlei published the artcileElectrochemical-Promoted Nickel-Catalyzed Oxidative Fluoroalkylation of Aryl Iodides, Recommanded Product: 1-(Difluoromethyl)naphthalene, the publication is Organic Letters (2021), 23(21), 8252-8256, database is CAplus and MEDLINE.

This work describes a general strategy for metal-catalyzed cross-coupling of fluoroalkyl radicals with aryl halides ArX (Ar = biphenyl-4-yl, benzothiophen-3-yl, benzodioxol-5-yl, etc.; X = Br, I) under electrochem. conditions. The contradiction between anodic oxidation of fluoroalkyl sulfinates NaSO₂CF₂H, NaSO₂CH₂F and cathodic reduction of low-valent nickel catalysts can be well addressed by paired electrolysis, allowing for direct introduction of fluorinated functionalities into aromatic systems.

Organic Letters published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C3H8N2S, Recommanded Product: 1-(Difluoromethyl)naphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Mu, Bing published the artcileSynthesis of symmetrical biaryls by cyclopalladated ferrocenylimine catalyzed ullmann-type coupling reaction, Related Products of naphthyridine, the publication is Henan Shifan Daxue Xuebao, Ziran Kexueban (2013), 41(5), 81-85, database is CAplus.

Cyclopalladated ferrocenylimine was tested as catalyst in the Ullmann-type coupling reaction in the presence of ¹Pr₂NEt as base and DMF as solvent under Ar conditions. The preparation of aromatic iodide comprises: diazotization reaction of substituted aniline with aqueous sodium nitrite solution in the presence of concentrated sulfuric acid to obtain substituted iodobenzene, adding with potassium iodide, placing in refrigerator for 2-3 h, adjusting with NaOH to alk., extracting with dichloromethane, drying with anhydrous magnesium sulfate. It offered excellent yields in the coupling reaction of electronically and structurally diverse aryl iodides. Herein we have developed a simple, efficient way to synthesize sym. biaryls.

Henan Shifan Daxue Xuebao, Ziran Kexueban published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zhao, Zujin published the artcileFluorescent, carrier-trapping dopants for highly efficient single-layer polyfluorene LEDs, Related Products of naphthyridine, the publication is Advanced Functional Materials (2007), 17(13), 2203-2210, database is CAplus.

Two fluorescent mols. with an alkynylanthracene core and pyrene end-cappers were synthesized and fully characterized. Carbazole moieties are introduced into one mol. at the C9 position of the fluorene linkages to enhance the hole-transport ability of the mol. and to reduce intermol. interactions. Both compounds exhibit high thermal stabilities and narrow energy bandgaps. Single-layer polymer light-emitting diodes (PLEDs) based on poly(9,9-dioctylfluorene) (PFO) doped with the synthesized compounds exhibit excellent performance. A PLED with 0.2% of dopant 7 had a high luminance efficiency of 10.7 ± 0.3 cd A^-1 as well as a brightness of 1400 cd m^-2 at a c.d. of 13 mA cm^-2, and a low turn on voltage (3.1 V) at a brightness of 10 cd m^-2. A maximum brightness of 20,500 ± 1400 cd m^-2 at 7 V was also measured. The high efficiency of the device’s performance is attributed to the good electron and hole trapping ability of the dopants, which possess suitable energy levels as compared to those of PFO.

Advanced Functional Materials published new progress about 18512-55-5. 18512-55-5 belongs to naphthyridine, auxiliary class Alkynyl,Anthracene, name is 9,10-Diethynylanthracene, and the molecular formula is C6H8N2O2, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Huang, Junmin published the artcileHighly efficient chromatographic resolution of α,α’-dihydroxybiaryls, Formula: C22H18O2, the publication is Organic Letters (2005), 7(26), 5821-5823, database is CAplus and MEDLINE.

Separation factors ≤115 were observed for the chromatog. resolution of many α,α’-dihydroxybiaryls with a single chiral stationary phase made from readily available amino acid derivatives The stationary phase works well for biphenyl-type compounds It works extremely well for larger bis-aromatic compounds, such as binaphthyl-type compounds

Organic Letters published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Formula: C22H18O2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Pitari, Giovanni Mario published the artcileExisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells, SDS of cas: 59973-80-7, the publication is Molecular Cancer Therapeutics (2006), 5(5), 1190-1196, database is CAplus and MEDLINE.

The nonsteroidal anti-inflammatory drug sulindac is metabolized to sulindac sulfone (exisulind), an antineoplastic agent that inhibits growth and induces apoptosis in solid tumors. In colon cancer cells, the antineoplastic effects of exisulind have been attributed, in part, to induction of cyclic guanosine 3′,5′-monophosphate (cGMP) signaling through inhibition of cGMP-specific phosphodiesterases, which elevates intracellular cGMP, and novel expression of cGMP-dependent protein kinase (PKG) Iβ, the presumed downstream effector mediating apoptosis. Here, inhibition of proliferation and induction of cell death by exisulind was dissociated from cGMP signaling in human colon cancer cells. Accumulation of intracellular cGMP produced by an exogenous cell-permeant analog of cGMP or a potent agonist of guanylyl cyclase C yielded cytostasis without cell death. Surprisingly, the antiproliferative effects of induced cGMP accumulation were paradoxically less than additive, rather than synergistic, when combined with exisulind. Further, although exisulind induced expression of PKG Iβ, it did not elevate intracellular cGMP and its efficacy was not altered by inhibition or activation of PKG I. Rather, PKG I induced by exisulind may mediate desensitization of cytostasis induced by cGMP. Thus, cytotoxic effects of exisulind are independent of cGMP signaling in human colon cancer cells. Moreover, combination therapies, including exisulind and agents that induce cGMP signaling, may require careful evaluation in patients with colon cancer.

Molecular Cancer Therapeutics published new progress about 59973-80-7. 59973-80-7 belongs to naphthyridine, auxiliary class Immunology/Inflammation,COX, name is Sulindac sulfone, and the molecular formula is C20H17FO4S, SDS of cas: 59973-80-7.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zhang, Ben published the artcilePreparation of two kinds of polyaspartic acid grafted copolymers and their scale inhibition performance, SDS of cas: 116-63-2, the publication is Huaxue Yanjiu (2013), 24(4), 420-424, database is CAplus.

Grafted copolymers polyaspartic acid/diethylenetriamine(denoted as PASP/DETA) and polyaspartic acid/1-amino-2-naphthol-4-sulfonic acid(denoted as PASP/1, 2, 4) were synthesized with urea, maleic anhydride, diethylenetriamine and 1-amino-2-naphthol-4-sulfonic acid as the starting materials. The chem. structure of as-synthesized products was analyzed by IR spectrometry; and their scale inhibition performance in industrial water was tested. Results show that PASP/DETA possesses excellent scale inhibition performance against Ca₃(PO₄)₂, and PASP/1, 2, 4possesses excellent scale inhibition performance against CaCO₃. When PASP/DETA and PASP/1, 2, 4 are combined at a concentration of 5 mg/L and 1.5 mg/ L, they have a scale inhibition efficiency of 95.4% against CaCO₃ and of 95.2% against Ca₃(PO₄)₂.

Huaxue Yanjiu published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C3H6O2, SDS of cas: 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Cheng, Ming published the artcileA Perylenediimide Tetramer-Based 3D Electron Transport Material for Efficient Planar Perovskite Solar Cell, Quality Control of 159-62-6, the publication is Solar RRL (2017), 1(5), n/a, database is CAplus.

A perylenediimide (PDI) tetramer-based three dimensional (3D) mol. material, termed SFX-PDI4, has been designed, synthesized, and characterized. The low-lying HOMO and LUMO energy levels, high electron mobility and good film-formation property make it a promising electron transport material (ETM) in inverted planar perovskite solar cells (PSCs). The device exhibits a high power conversion efficiency (PCE) of 15.3% with negligible hysteresis, which can rival that of device based on PC₆₁BM. These results demonstrate that three dimensional PDI-based mol. materials could serve as high performance ETMs in PSCs.

Solar RRL published new progress about 159-62-6. 159-62-6 belongs to naphthyridine, auxiliary class Other Aromatic Heterocyclic,Spiro, name is Spiro[fluorene-9,9′-xanthene], and the molecular formula is C25H16O, Quality Control of 159-62-6.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem