Heterocyclic Building Blocks-Naphthyridine

Wood, Natasha C. L. published the artcileMediated electron transfer from lithium investigated voltammetrically in tetrahydrofuran: why are some mediators more effective reducing reagents than others?, SDS of cas: 2960-93-2, the publication is Journal of Physical Organic Chemistry (2007), 20(10), 732-742, database is CAplus.

A study of a range of aromatic mols. was studied electrochem. to determine what makes an effective reducing mediator. With the aim of developing a better understanding of electron transfers (ETs) mediated from Li in functional group reduction, single ET reactions are reported. Typical reaction conditions involved the use of aromatic mediators such as naphthalene, anthracene, 4,4′-di-tert-butyl-1,1′-biphenyl (DBB) with Li metal in THF at -78°. The results of these experiments showed that some mediators were more effective reducing reagents than others. Cryoelectrochem. procedures are used to mimic the conditions of the SET (single electron transfer) reactions to study the exact nature and role of the mediator formed upon ET. Electrogenerated and stabilized radical anions of anthracene at -78° mediate the reduction of organic substrates, whereas the more reactive dianion is quickly protonated and therefore unable to act as an ET reagent; direct electrochem. reduction of the sulfide, Ph 3-phenylpropyl sulfide (RSPh) gives the thiol, thiophenol, and propylbenzene whereas mediated reduction gives the dimer, di-Ph disulfide and Pr benzene. The possibility to selectively reduce a substrate with either a single electron or with 2 electrons is possible by using either the radical anion (mediated) or via the direct electroreduction DBB and naphthalene (both single electron accepting species only) are the most effective reducing reagents. Anthracene and other 2-electron accepting species only showed effective reducing ability when a stoichiometric amount of Li was used therefore preventing the over-reduction to the dianion.

Journal of Physical Organic Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C18H21BO4, SDS of cas: 2960-93-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Zuo, Zongyan published the artcileSpiro-substitution effect of terfluorenes on amplified spontaneous emission and lasing behaviors, SDS of cas: 159-62-6, the publication is Journal of Materials Chemistry C: Materials for Optical and Electronic Devices (2018), 6(16), 4501-4507, database is CAplus.

In order to investigate the inherent differences between spirofluorenes, two typical spirocycle models, spiro[fluorene-9,9′-xanthene] (SFX) and spirobiflourene (SBF), were chosen to construct four spiro-terfluorenes (DSFX-OSFX, DSBF-OSFX, DOSFX-SFX and DOSFX-SBF) to investigate the effect of spirocycle substitution on photophys. and stimulated emission properties. The terfluorenes have similar absorption and photoluminescence properties. While the DOSFX-SBF film displays the best ASE properties with a threshold of 1.81 μJ cm^-2, the lasing threshold of the 1-D DFB laser based on DOSFX-SBF is lowered to 0.85 μJ cm^-2. These results indicate that the type of spirofluorene has a dramatic influence on stimulated emission properties and spiro terfluorenes have potential applications in organic lasers.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about 159-62-6. 159-62-6 belongs to naphthyridine, auxiliary class Other Aromatic Heterocyclic,Spiro, name is Spiro[fluorene-9,9′-xanthene], and the molecular formula is C13H15NO6S, SDS of cas: 159-62-6.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Verhoog, Stefan published the artcileSilver-Mediated ¹⁸F-Labeling of Aryl-CF₃ and Aryl-CHF₂ with ¹⁸F-Fluoride, Formula: C11H8F2, the publication is Synlett (2016), 27(1), 25-28, database is CAplus.

We report the synthesis of [¹⁸F]arylCF₃ and [¹⁸F]arylCHF₂ derivatives from arylCF₂Br and arylCHFCl precursors applying a silver-mediated halogen exchange with [¹⁸F]fluoride. In the absence of Ag(I)OTf, no reaction takes place at room temperature for both classes of substrates; this result demonstrates the beneficial role of silver(I) as a means to induce ¹⁸F-incorporation under very mild conditions.

Synlett published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C9H9BrO2, Formula: C11H8F2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Sancho, Raquel published the artcileA (4R)-hydroxy-L-proline-derived chiral scaffold and its oligomers as chiral selectors in liquid chromatography chiral stationary phases for enantioseparation, Related Products of naphthyridine, the publication is Journal of Separation Science (2006), 29(6), 905-914, database is CAplus and MEDLINE.

The chromatog. behavior of a poly-L-proline-derivatized chiral stationary phase (CSP) is compared to the corresponding single proline-derived CSP. Structurally diverse racemic test compounds and mobile phases, including normal- and RP conditions, were used. Although the application domain of the poly-L-proline-derived CSP (CSP-3) was considerably restricted, this CSP showed a higher retention and a slightly broader application domain than the monomeric analog (CSP-1) when heptane/2-PrOH was used as mobile phase. The presence of an alc. in the mobile phase was essential for enantioseparation in the poly-L-proline-derived CSP when normal-phase conditions were applied.

Journal of Separation Science published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Liu, Bicheng published the artcileA sensitive fluorescent assay for the determination of parathion-methyl using AHNSA probe with MnO₂ nanosheets, Computed Properties of 116-63-2, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2021), 119146, database is CAplus and MEDLINE.

In this paper, a novel fluorescence assay has been constructed for the determination of parathion-Me (PM) by using 4-amino-3-hydroxy-1-naphthalenesulfonic acid (AHNSA) as probe. MnO₂ nanosheets (MnO₂ NS) could quench the fluorescence of AHNSA, while Mn²⁺, the reduction product of MnO₂ NS, has no influence on it, resulting in fluorescence recovery. This is because that MnO₂ NS have oxidized characteristic, and they can react with choline (TCh), which is the product of acetylthiocholine (ATCh) catalyzed by acetylcholinesterase (AChE). In the presence of OPs, the activity of AChE was inhibited, accompanied by the restraint of the redox reaction of MnO₂ NS, therefore the fluorescence of AHNSA was quenched. Under the optimized exptl. conditions, a linear range of PM was determined to be 0.4-40 ng/mL (R² = 0.997) by the proposed method with the limit of detection for 0.18 ng/mL (S/N = 3). The assay was successfully applied to the determination of PM in lake water, which average recoveries were between 86.5% and 114.4%.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Computed Properties of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Fang, Jingxian published the artcileGraphene-Oxide-Promoted Direct Dehydrogenative Coupling Reaction of Aromatics, HPLC of Formula: 2960-93-2, the publication is Asian Journal of Organic Chemistry (2018), 7(2), 355-358, database is CAplus.

Graphene oxide, which is a popular 2D carbon material, promoted a direct dehydrogenative coupling reaction of aromatics Homo-coupling and cross-coupling reactions were achieved in good yields in the presence of graphene oxide. This strategy was simple and did not required any other additives, such as acid/base or ligand. The reaction was easily scaled up to gram level.

Asian Journal of Organic Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, HPLC of Formula: 2960-93-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Mosquera, Angeles published the artcileSynthesis of Axially Chiral 1,1′-Binaphthalenes by Palladium-Catalysed Cross-Coupling Reactions of Triorganoindium Reagents, Recommanded Product: 2,2′-Dimethoxy-1,1′-binaphthalene, the publication is European Journal of Organic Chemistry (2013), 2013(13), 2555-2562, database is CAplus.

1,1′-Binaphthalenes and heterocyclic analogs can be efficiently prepared by palladium-catalyzed cross-coupling reactions between tri(1-naphthyl)indium reagents and 1-halonaphthalenes and haloisoquinolines. The reactions were usually carried out in THF at 80° with a slight excess of the indium reagent (40 mol-%) and a low catalyst loading (4 mol-% Pd) to afford the cross-coupling products in good yields (45-99 %). The method allows the synthesis of sterically hindered 2-substituted and 2,2′-disubstituted 1,1′-binaphthalenes and naphthylisoquinolines. In addition, the coupling reactions can be performed enantioselectively and the best enantiomeric excesses were obtained by using the chiral amino-phosphane ferrocenyl ligand (R,S)-PPFA.

European Journal of Organic Chemistry published new progress about 2960-93-2. 2960-93-2 belongs to naphthyridine, auxiliary class Naphthalene,Ether,Other MOF ligands,Organic ligands for MOF materials, name is 2,2′-Dimethoxy-1,1′-binaphthalene, and the molecular formula is C22H18O2, Recommanded Product: 2,2′-Dimethoxy-1,1′-binaphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Sahoo, Anupam published the artcileA Combined Process for the Degradation of Azo-Dyes and Efficient Removal of Aromatic Amines Using Porous Silicon Supported Porous Ruthenium Nanocatalyst, Quality Control of 116-63-2, the publication is ACS Applied Nano Materials (2018), 1(9), 5169-5178, database is CAplus.

Herein, the authors present a facile route for the preparation of porous Si supported porous Ru nanoparticle system (Si@p-RuNP) for efficient removal of azo-based dyes and aromatic amines from wastewater. The synthesized nanoparticles were characterized using different anal. techniques including high-resolution TEM, XPS, field-emission SEM, powder x-ray diffraction, Brunauer-Emmett-Teller anal., etc. The Si@p-RuNP nanocatalytic system exhibits dual catalytic behavior for the reduction of -N=N- bond and oxidation of aromatic amines in aqueous solution The porous nanostructured Si@p-RuNP exhibits excellent degradation efficacy for Congo red dye (44 cycles in 1 h) as compared to its solid analog Si@RuNP (24 cycles in 1 h) in the presence of NaBH₄. Also, the present nanocatalyst mimics the peroxidase-like activity toward oxidation of various aromatic amines to their corresponding polyamines at pH 5.0 in the presence of H₂O₂ as an oxidant. Polyamines being insoluble in H₂O offers a simple and convenient strategy for the elimination of H₂O-soluble aromatic amines. The present process is convenient, efficient, and cost-effective and generates a small amount of solid waste as compared to the existing processes. Thus, the authors envision that the present unique nanocatalyst system can be useful for the removal of toxic amines from effluent toward solving the problem of textile-based industrial wastewater.

ACS Applied Nano Materials published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Quality Control of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Kumar, Sunil published the artcileSynthesis, characterization and evaluation for anticonvulsant activity of acetylnaphthalene and substituted acetylenaphthalene derivative of heterocyclic compounds, Synthetic Route of 116-63-2, the publication is Pharma Innovation (2013), 1(11), 90-101, database is CAplus.

A series of acetyl- and acetoxynaphthalenes was prepared by Mannich reaction with secondary amines and CH₂O. In this reaction the Ac group served as he H active compound The novel compounds were tested for anticonvulsant activity using pentylenetetrazole (scPTZ) test. Some of the compounds showed significant anticonvulsant activity.

Pharma Innovation published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Synthetic Route of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Anjali published the artcileSynthesis, characterisation, antioxidant and antimicrobial activity of isatin derivatives, Name: 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, the publication is International Research Journal of Pharmacy (2019), 10(9), 223-230, database is CAplus.

In the present study some novel Schiff bases of isatin I [R = OH, 2-O₂NC₆H₄, 2-Cl-4-O₂NC₆H₃, etc.] were synthesized by condensation of isatin mol. with anilines after performing the mol. docking and ADME prediction. Some new Schiff bases of isatin I were prepared in order to study the antibacterial, antifungal and antioxidant properties. The isatin was synthesized by Sandmeyer method and then its derivatives I were synthesized after obtaining significant results from mol. docking and ADME prediction. The structures of the synthesized compounds I were confirmed by means of IR, ¹H-NMR and elemental anal. Synthesized compounds I were screened for antioxidant activity, among which I [R = 2-Cl-4-O₂NC₆H₃] showed potent activity as antioxidant. Synthesized compounds I showed broad spectrum of antibacterial and antifungal activities.

International Research Journal of Pharmacy published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Name: 4-Amino-3-hydroxynaphthalene-1-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem