Tag: M.W=150-200

Patra, Kamaless’s team published research in Organometallics in 41 | CAS: 14903-78-7

Organometallics published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Category: naphthyridine.

Patra, Kamaless published the artcileA Protic Mn(I) Complex Based on a Naphthyridine-N-oxide Scaffold: Protonation/Deprotonation Studies and Catalytic Applications for Alkylation of Ketones, Category: naphthyridine, the publication is Organometallics (2022), 41(14), 1836-1846, database is CAplus.

A Mn(I) complex (1) bearing a proton responsive hydroxy unit on 1,8-naphthyridine-N-oxide scaffold (L1H) was synthesized. The mol. structure of 1 revealed the lactim form of the ligand. The corresponding deprotonated lactam complexes [18-C-6-K路2] and 3 were prepared and structurally characterized. The acid-base equilibrium between the lactim and lactam forms was studied by 1H NMR and UV-visible spectra. The catalytic efficiency of 1 was evaluated by performing 伪-alkylation reaction of ketones with primary alcs. The scope of the 伪-alkylation reaction is broad in terms of both ketones and alcs. The efficacy of the protic catalyst is demonstrated in the alkylation of the bioactive steroids progesterone and pregnenolone. A controlled catalyst [Mn(L2)(CO)3Br] (4), which is structurally similar to 1 but devoid of the proton responsive hydroxy unit, shows significantly reduced catalytic efficiency validating the crucial role of the hydroxy functionality in 1. Kinetic study, control reactions, and D labeling experiments were conducted to gain mechanistic insights.

Organometallics published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Category: naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Raj Sinha, Deo’s team published research in Journal of the Indian Chemical Society in 56 | CAS: 14903-78-7

Journal of the Indian Chemical Society published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Quality Control of 14903-78-7.

Raj Sinha, Deo published the artcileNaphthyridines reactivity of methyl groups: new cyanine dyes from 2,7-dimethyl- and 4,7-dimethyl-1,8-naphthyridines, Quality Control of 14903-78-7, the publication is Journal of the Indian Chemical Society (1979), 56(2), 164-7, database is CAplus.

The reactivity of the 4-Me in 4,7-dimethyl-1,8-naphthyridine (I) [14759-23-0] is greater than the 7-Me towards condensation with m-nitrobenzladehyde [99-61-6]. Cyanine and styryl dyes derived from I and from 2,7-dimethyl-1,8-naphthyridine [14903-78-7] were prepared and their structures established. The trimethine dyes were found to be useless as sensitizers for Ag halide emulsions.

Journal of the Indian Chemical Society published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Quality Control of 14903-78-7.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Paudler, William W.’s team published research in Journal of Heterocyclic Chemistry in 4 | CAS: 14903-78-7

Journal of Heterocyclic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Recommanded Product: 2,7-Dimethyl-1,8-naphthyridine.

Paudler, William W. published the artcileSkraup synthesis and nuclear magnetic resonance spectra of some methylnaphthyridines, Recommanded Product: 2,7-Dimethyl-1,8-naphthyridine, the publication is Journal of Heterocyclic Chemistry (1967), 4(2), 284-9, database is CAplus.

Some mono- and dimethylnaphthyridines were prepared by the application of the Skraup reaction to various 2- and 4-aminopyridines. The proton N.M.R. spectral data assignments are reported. The chem. shifts of the Me protons are calculated

Journal of Heterocyclic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Recommanded Product: 2,7-Dimethyl-1,8-naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Paudler, William W.’s team published research in Journal of Heterocyclic Chemistry in 4 | CAS: 14903-78-7

Journal of Heterocyclic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Name: 2,7-Dimethyl-1,8-naphthyridine.

Paudler, William W. published the artcileNaphthyridine chemistry. VIII. Mass spectra of the 1,x-naphthyridines and some of their methyl derivatives, Name: 2,7-Dimethyl-1,8-naphthyridine, the publication is Journal of Heterocyclic Chemistry (1967), 4(4), 547-54, database is CAplus.

The mass spectra of the four parent 1,x-naphthyridines, the 2-, 3-, and 4-monomethyl-1,5-, 1,6-, and 1,8-naphthyridines, seven dimethyl-1,8-naphthyridines, and one trimethyl-1,8-naphthyridine are reported. Evidence for an azatropylium ion intermediate in the fragmentation of the methyl compounds is presented. The fragmentation modes of the naphthyridines are similar to those for the quinolines in addition to several new processes.

Journal of Heterocyclic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Name: 2,7-Dimethyl-1,8-naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Weber, E.’s team published research in Journal fuer Praktische Chemie/Chemiker-Zeitung in 337 | CAS: 14903-78-7

Journal fuer Praktische Chemie/Chemiker-Zeitung published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C26H41N5O7S, SDS of cas: 14903-78-7.

Weber, E. published the artcileBenzo condensed crown ethers containing 1,8-naphthyridine or 4-pyridone units. Synthesis and complex formation with organic guest molecules, SDS of cas: 14903-78-7, the publication is Journal fuer Praktische Chemie/Chemiker-Zeitung (1995), 337(6), 451-5, database is CAplus.

New crown compounds, e.g., I, comprising, beside o-phenylene groups, 1,8-naphthyridine or 4-pyridone groups as characteristic building units are synthesized. They form numerous stoichiometric crystalline complexes with uncharged organic mols. including alcs., nitro compounds and other dipolar-aprotic solvents, as well as cyclic ethers and aromatic hydrocarbons. Properties of complex formation and host-guest stoichiometries are discussed in comparison with parent host analogs.

Journal fuer Praktische Chemie/Chemiker-Zeitung published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C26H41N5O7S, SDS of cas: 14903-78-7.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Motohashi, Hirotaka’s team published research in Journal of Organic Chemistry in 84 | CAS: 53731-26-3

Journal of Organic Chemistry published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, Recommanded Product: 1-(Difluoromethyl)naphthalene.

Motohashi, Hirotaka published the artcileLigand-Less Iron-Catalyzed Aromatic Cross-Coupling Difluoromethylation of Grignard Reagents with Difluoroiodomethane, Recommanded Product: 1-(Difluoromethyl)naphthalene, the publication is Journal of Organic Chemistry (2019), 84(10), 6483-6490, database is CAplus and MEDLINE.

Iron-catalyzed cross-coupling difluoromethylations of the Grignard reagents with difluoroiodomethane provide various aromatic difluoromethyl products in good yields, not employing sterically demanding ligands. Difluoromethylations proceed within 30 min at -20 °C with 2.0 equiv of the Grignard reagents and FeCl3 or Fe(acac)3 (2.5 mol %). Mechanistic investigations clarify difluoromethyl radical intervention; Fe(0) ate is initially generated. Single electron transfer from Fe(0) ate to difluoroiodomethane takes place. Recombination with aryl groups gives Ar-CF2Hs. The catalyst can be regenerated by the Grignard reagents.

Journal of Organic Chemistry published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, Recommanded Product: 1-(Difluoromethyl)naphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Matheis, Christian’s team published research in Organic Letters in 16 | CAS: 53731-26-3

Organic Letters published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, Application of 1-(Difluoromethyl)naphthalene.

Matheis, Christian published the artcileSandmeyer Difluoromethylation of (Hetero-)Arenediazonium Salts, Application of 1-(Difluoromethyl)naphthalene, the publication is Organic Letters (2014), 16(22), 5984-5987, database is CAplus and MEDLINE.

A Sandmeyer-type difluoromethylation process has been developed that allows the straightforward conversion of (hetero)arenediazonium salts into the corresponding difluoromethyl (hetero)arenes under mild conditions. The actual difluoromethylating reagent, a difluoromethyl-copper complex, is formed in situ from copper thiocyanate and TMS-CF2H. The diazonium salts are either preformed or generated in situ from broadly available aromatic amines.

Organic Letters published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, Application of 1-(Difluoromethyl)naphthalene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Fu, Wen-Fu’s team published research in Inorganic Chemistry in 49 | CAS: 14903-78-7

Inorganic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Related Products of naphthyridine.

Fu, Wen-Fu published the artcileSynthesis, characterization, photoinduced isomerization, and spectroscopic properties of vinyl-1,8-naphthyridine derivatives and their copper(I) complexes, Related Products of naphthyridine, the publication is Inorganic Chemistry (2010), 49(10), 4524-4533, database is CAplus and MEDLINE.

Acetylamino-substituted 2-pyridinylvinyl-1,8-naphthyridine ligands and their copper(I) phosphine mono- and binuclear complexes were prepared and characterized by x-ray crystal structure determination A series of 2-(2-pyridinylvinyl) 1,8-naphthyridine ligands, 7-acetamido-2-(6-acetamido-2-pyridinylethenyl)-4-methyl-1,8-naphthyridine (L1), 2-(6-acetamido-2-pyridylethenyl)-1,8-naphthyridine (L2), 7-(6-acetamido-2-pyridinylethenyl)-5-methyl-1,8-naphthyridin-2(1H)-one (L3), 2-(2-diacetylamino-3-pyridinylethenyl)-7-(diacetylmethylene)-7,8-dihydro-1,8-naphthyridine (L4), and 2-(2-diacetylamino-3-pyridinylethenyl)-7-acetylpyrrolo[1,2-a]-1,8-naphthyridine (L5), as well as copper(I) phosphine complexes I, [CuL1(PCy3)](BF4) (1, I·BF4, M, Y1 void, Y = tricyclohexylphosphine), [Cu2L1(PPh3)4](BF4)2 [2, I·2BF4, M = Cu, Y = Y1 = (PPh3)2,], [Cu2L1(dppm)](BF4)2 (3, I·2BF4, M = Cu, Y-Y1 = dppm), and [Cu2(L1)(dcpm)](BF4)2 [4, I·2BF4, M = Cu, Y-Y1 = bis(dicyclohexylphosphino)methane] were prepared All these compounds, except for L1 and L2, were characterized by single crystal x-ray diffraction anal., and a comprehensive study of their spectroscopic properties involving TD-DFT theor. calculations is presented. An intramol. 1,3-hydrogen transfer takes place during the formation of L3 and L4, which in the case of the latter plays an important role in the 1,5-dipolar cyclization into L5. The spectral changes that originate from an intramol. charge transfer (ICT) in the form of a πpy→π*napy transition can be tuned through acid/base-controlled switching for L1-L3. Ligands L1-L3, complexes 1 and 2 undergo photochem. (E)-(Z)-double bond isomerization under 365 nm light irradiation due to their flexible structures. Quantum chem. calculations revealed that the dinuclear complexes with structural asymmetry exhibit different metal-to-ligand charge-transfer transitions.

Inorganic Chemistry published new progress about 14903-78-7. 14903-78-7 belongs to naphthyridine, auxiliary class 6.6_Aromatics,Naphthyridines, name is 2,7-Dimethyl-1,8-naphthyridine, and the molecular formula is C10H10N2, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Iwamoto, Hiroaki’s team published research in Journal of the American Chemical Society in 142 | CAS: 53731-26-3

Journal of the American Chemical Society published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, COA of Formula: C11H8F2.

Iwamoto, Hiroaki published the artcileCleavage of C(sp3)-F Bonds in Trifluoromethylarenes Using a Bis(NHC)nickel(0) Complex, COA of Formula: C11H8F2, the publication is Journal of the American Chemical Society (2020), 142(45), 19360-19367, database is CAplus and MEDLINE.

The first example of the oxidative addition of a C(sp3)-F bond in trifluoromethylarenes to a nickel(0) complex is described. A nickel(0) complex that bears two N-heterocyclic carbene (NHC) ligands of low steric demand is able to cleave C(sp3)-F bonds of trifluoromethylarenes to afford the corresponding trans-difluorobenzyl nickel(II) fluoride complexes. Isolation and characterization studies suggested that the cleavage of the C(sp3)-F bond proceeds via an η2-arene nickel(0) complex. Taking advantage of the reactivity of these nickel(II) fluoride complexes, we developed a catalytic hydrodefluorination of trifluoromethylarenes using hydrosilanes. A computational study indicated that the electron-rich nickel(0) center supported by two relatively small NHC ligands cleaves the C(sp3)-F bond via a syn-SN2′ mechanism.

Journal of the American Chemical Society published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C11H8F2, COA of Formula: C11H8F2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Serizawa, Hiroki’s team published research in Organic Letters in 18 | CAS: 53731-26-3

Organic Letters published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C14H19NO8, Formula: C11H8F2.

Serizawa, Hiroki published the artcileCopper-Catalyzed Difluoromethylation of Aryl Iodides with (Difluoromethyl)zinc Reagent, Formula: C11H8F2, the publication is Organic Letters (2016), 18(15), 3686-3689, database is CAplus and MEDLINE.

The combination of difluoroiodomethane and zinc dust or diethylzinc can readily lead to (difluoromethyl)zinc reagents. Therefore, the first copper-catalyzed difluoromethylation of aryl iodides with the zinc reagents is accomplished to afford the difluoromethylated arenes. The reaction proceeds efficiently through the ligand/activator-free operation without addition of ligands for copper catalyst (e.g., phen and bpy) and activators for zinc reagent (e.g., KF, CsF, and NaO-t-Bu). Moreover, transmetalation of the CF2H group from zinc reagent to copper catalyst proceeds even at room temperature to form the cuprate [Cu(CF2H)2]–.

Organic Letters published new progress about 53731-26-3. 53731-26-3 belongs to naphthyridine, auxiliary class Difluoromethyl,Fluoride,Naphthalene, name is 1-(Difluoromethyl)naphthalene, and the molecular formula is C14H19NO8, Formula: C11H8F2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem