Tag: M.W=200-250

Patil, A. A. published the artcilePeriodical status of plant available silicon as influenced by silicon extractants and levels of silicon in alkaline soils, Product Details of C10H9NO4S, the publication is International Journal of Chemical Studies (2017), 5(6Pt.C), 166-173, database is CAplus.

An incubation study was conducted by using calcium silicate as a source of silicon in alk. soils of order Inceptisols and Vertisols. The purpose of study was to know the periodical status of plant available silicon (PAS) as influenced by silicon extractants and levels of silicon in alk. soils. The experiment was laid out in factorial completely randomized design having seventy treatment combinations replicated thrice. The main treatments were ten silicon extractants and sub treatments were levels of silicon. The periodical status of PAS in Inceptisols and Vertisols showed bell shaped curve throughout incubation study. The PAS status increased from 0 to 40 day and then decreased from 60 to 100 day. The maximum PAS was recorded at 40 day. The silicon extractant 0.1 M Citric acid (1:50) and application of GRDF + Si @ 200 kg ha^-1 recorded significantly highest PAS status in Inceptisols and Vertisols throughout incubation study.

International Journal of Chemical Studies published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Product Details of C10H9NO4S.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Atahan, Alparslan published the artcile1-Amino-2-hydroxy-4-naphthalenesulfonic acid based Schiff bases or naphtho[1,2-d]oxazoles: Selective synthesis and photophysical properties, Formula: C10H9NO4S, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2015), 61-67, database is CAplus and MEDLINE.

A series of Schiff base and naphtho[1,2-d]oxazole derivatives were selectively synthesized via condensation reaction of 1-amino-2-hydroxy-4-naphthalenesulfonic acid and benzaldehyde derivatives at same conditions. The synthesized compounds were then characterized by using ¹HNMR, ¹³CNMR, FTIR spectroscopies and elemental analyses. It was seen that the Schiff bases e. g., I, generated in the presence of OH group at ortho position of benzaldehyde derivatives However, the products were naphtho[1,2-d]oxazoles e. g., II, in other cases. Then, the synthesized compounds were photophys. investigated by UV absorption and fluorescence emission spectroscopies. As a result, these Schiff bases have shown long wavelength absorption (λ_max: 386 nm) and emission (λ_max: 429-437 nm) effect while synthesized naphtho[1,2-d]oxazole derivatives have a set of absorption (λ_max: about 296, 308, 320 nm) and emission maxima (λ_max: 378-395 nm) at lower wavelength.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Formula: C10H9NO4S.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Tarkuc, Simge published the artcileThe relationship between molecular structure and electronic properties in dicyanovinyl substituted acceptor-donor-acceptor chromophores, Name: 9,10-Diethynylanthracene, the publication is Tetrahedron (2017), 73(33), 4994-5004, database is CAplus.

In this contribution the authors describe a combined exptl. and theor. study of the relation between the mol. structure and the electronic properties of conjugated donor-acceptor type chromophores for light-harvesting applications. A series of model systems was synthesized where a central anthracene (electron donor) is connected to dicyanovinyl units (electron acceptor) through a π-conjugated spacer. The study of the redox and optical properties of these chromophores and of reference compounds without dicyanovinyl units allows the authors correlate the electronic properties to the presence of the electron withdrawing groups and the mol. conformation. Comparison with calculated electronic structure shows that the construction of chromophores that consist of electron donating and accepting units does not always follow the simple rules that are generally used in the design of such mols. The results show a subtle relation between the charge transfer character and the geometry of the mols. In some cases this leads to significant contribution of charge transfer excitation to the absorption spectra of some chromophores while such contributions are completely absent in others.

Tetrahedron published new progress about 18512-55-5. 18512-55-5 belongs to naphthyridine, auxiliary class Alkynyl,Anthracene, name is 9,10-Diethynylanthracene, and the molecular formula is C16H14O6, Name: 9,10-Diethynylanthracene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Abu-Dief, Ahmed M. published the artcileTargeting ctDNA binding and elaborated in-vitro assessments concerning novel Schiff base complexes: Synthesis, characterization, DFT and detailed in-silico confirmation, Formula: C10H9NO4S, the publication is Journal of Molecular Liquids (2021), 114977, database is CAplus.

Two novel complexes for Zn²⁺ and VO²⁺ ions, were prepared from tridentate dibasic chelating Schiff base ligand. 1-((3,5-di-tert-butyl-2-hydroxybenzylidene)amino)naphthalen-2-ol-5-sodium sulfonate (DSHN), was the ligand used in this study. Alternative spectral tools were applied to elucidate structural composition of new compounds Also, geometry optimization for all synthesizes was conducted by Gaussian09 program via DFT method, to obtain optimal structures and essential parameters. Moreover, the biochem. behavior for all synthesizes, was explored based on tested reactivity against various microbial strains and cancer cells (HCT-116, MCF-7, and HepG-2). The two complexes exhibited interestingly anti-proliferative potential against human cancer cell lines. The antioxidant behavior of the two complexes was studied by DPPH and SOD assays. Particularly, Zn(II) and VO(II) complexes presented more enhanced antimicrobial and anticancer features compared to the free ligand (DSHN), with superiority for VO(II) complex. The binding nature of two complexes with calf thymus DNA (ctDNA), was examined by various methods as, spectrophotometry, viscosity and gel electrophoresis. Their binding efficiency with ctDNA was proposed to be just intercalation or replacement mode. This in-vitro assay was confirmed by in-silico simulation vs. 1cca, 1jnx, 1smp, 2 h80 and 5ajh as the co-crystals for selected pathogen-proteins, which attribute to microbes and cancer cells.

Journal of Molecular Liquids published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Formula: C10H9NO4S.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Eissa, Ibrahim H. published the artcileDesign and Discovery of Novel Quinoxaline Derivatives as Dual DNA Intercalators and Topoisomerase II Inhibitors, Quality Control of 116-63-2, the publication is Anti-Cancer Agents in Medicinal Chemistry (2018), 18(2), 195-209, database is CAplus and MEDLINE.

Backgroun/Methods: In attempt to develop new potent antitumor agents, a series of quinoxaline derivatives was designed and synthesized. The novel compounds were tested in vitro for their antiproliferative activities against HePG2, MCF7 and HCT116 cell lines. Addnl., DNA binding affinities as well as DNAtop II inhibitory activities of the synthesized compounds were investigated as potential mechanism for anticancer activity. Compounds 13, 15, 16 and 19 exhibited good cytotoxicity activities against the three cell lines (IC50 ranging from 7.6 to 32.4 muM) comparable to that of doxorubicin (IC50 = 9.8 muM). Results: Interestingly, the results of DNA binding and DNAtop II inhibition assays were in agreement with those of the cytotoxicity tests, where the most potent anticancer compounds showed good DNA binding affinities (IC50 ranging from 25.1 to 32.4 muM) and DNAtop II inhibitory activities (IC50 ranging from 6.4 to 15.3 muM) comparable to those of doxorubicin (IC50 = 28.1 and 3.8 muM, resp.). Furthermore, mol. docking studies were carried out for the new compounds in order to investigate their binding pattern with the prospective target, DNAtop II complex (PDBcode: 3qx3).

Anti-Cancer Agents in Medicinal Chemistry published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Quality Control of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Noser, Ahmed A. published the artcileSynthesis, in silico and in vitro assessment of new quinazolinones as anticancer agents via potential AKT inhibition, Computed Properties of 116-63-2, the publication is Molecules (2020), 25(20), 4780, database is CAplus and MEDLINE.

A series of novel quinazolinone I [ R = 4-carboxyphenyl, 3-carboxyphenyl, 4-hexadecoxycarbonylphenyl, etc.] was synthesized and examined for their cytotoxicity to HepG2, MCF-7, and Caco-2 in an MTT assay. Among these derivatives, compounds I [ R = 4-hexadecoxycarbonylphenyl] and I [ R = (2-methylbutanoyl)oxyphenyl] exhibited significant cytotoxic activity against Caco-2, HepG2, and MCF-7 cancer cells. Compound I [ R = 4-hexadecoxycarbonylphenyl] had more significant inhibitory effects than compound I [ R = (2-methylbutanoyl)oxyphenyl] on Caco-2, HepG2, and MCF-7 cell lines, with IC₅₀ values of 23.31 ± 0.09, 53.29 ± 0.25, and 72.22 ± 0.14μM, resp. The AKT pathway was one of human cancer’s most often deregulated signals. AKT was also overexpressed in human cancers such as glioma, lung, breast, ovarian, gastric, and pancreas. A mol. docking study was performed to analyze the inhibitory action of newly synthetic quinazolinone derivatives against Homo sapiens AKT1 protein. Mol. docking simulations were found to be in accordance with in-vitro studies, and hence supported the biol. activity. The results suggested that compounds I [ R = 4-hexadecoxycarbonylphenyl] and I [ R = (2-methylbutanoyl)oxyphenyl] could be used as drug candidates for cancer therapy via its potential inhibition of AKT1 as described by docking study.

Molecules published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Computed Properties of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Garcia-Gonzalez, Ma. Carmen published the artcilePairing multicomponent stators with aromatic rotators for new emissive molecular rotors, SDS of cas: 18512-55-5, the publication is Organic & Biomolecular Chemistry (2021), 19(15), 3404-3412, database is CAplus and MEDLINE.

We demonstrate here that the Ugi-Sonogashira protocol can be successfully used to obtain five new mol. rotors such as I with strong emission. The mol. rotors have been synthesized by combining multicomponent stators derived from Ugi reactions of 4-iodoaniline, trans-cinnamaldehyde, 2-bromobenzoic acid, and cyclohexyl or tert-Bu isonitriles with dialkyne axles with phenylene, p-xylene, naphthalene and anthracene linkers. The synthesized conjugated rotors are highly fluorescent (Φ_f = 0.39 to Φ_f = 0.10), and changes in their emission were observed upon variations of the surrounding media, particularly on changes in solvents leading to aggregation or on increases in solvent viscosity.

Organic & Biomolecular Chemistry published new progress about 18512-55-5. 18512-55-5 belongs to naphthyridine, auxiliary class Alkynyl,Anthracene, name is 9,10-Diethynylanthracene, and the molecular formula is C18H10, SDS of cas: 18512-55-5.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Matsumi, Noriyoshi published the artcileSynthesis of novel σ-π conjugated polymers by alternating boration copolymerization between 1,2-diethynyl-1,1,2,2-tetramethyldisilane and aromatic diynes, Related Products of naphthyridine, the publication is Polymer Journal (Tokyo, Japan) (2001), 33(5), 383-386, database is CAplus.

Novel σ-π conjugated polymers were prepared by alternating boration copolymerization between 1,2-diethynyl-1,1,2,2-tetramethyldisilane and aromatic diynes using diphenylbromoborane. The gel permeation chromatog. anal. (GPC) showed that the number average mol. weights (M_n) of the obtained polymers were several thousands. For example, M_n of the polymer produced from 2,7-diethynylfluorene was 5700 (yield 30%). The polymers were soluble in common organic solvents such as THF, chloroform and dichloromethane. The polymer having the fluorene unit was moderately fluorescent. The structures of the polymers were supported by ¹H NMR, ¹¹B NMR, ²⁹Si NMR, and IR spectra.

Polymer Journal (Tokyo, Japan) published new progress about 18512-55-5. 18512-55-5 belongs to naphthyridine, auxiliary class Alkynyl,Anthracene, name is 9,10-Diethynylanthracene, and the molecular formula is C18H10, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Ju, Jin Uk published the artcileSynthesis and characterization of a new ethynyl-linked alternating anthracene/fluorene copolymer for organic thin film transistor, Synthetic Route of 18512-55-5, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (2009), 47(6), 1609-1616, database is CAplus.

A new p-type conjugated copolymer, poly(9,10-diethynylanthracene-alt-9,9-didodecylfluorene) (PDADF), which is composed of ethynyl-linked alternating anthracene/fluorene, is synthesized via a palladium(II)-catalyzed Sonogashira coupling reaction with 9,10-diethynylanthracene and 2,7-diiodo-9,9-didodecyl-fluorene. The obtained polymer is confirmed by FTIR, ¹H-NMR, ¹³C-NMR and elemental anal. The PDADF had very good solubility in organic solvents such as chloroform and had a weight average mol. weight of 29,300 with a polydispersity index of 1.29. The PL maximum of the polymer was found at 533 and 568 nm for a solution and 608 nm for film, resp. The HOMO energy of the polymer is -5.62 eV as measured via cyclic voltammetry (CV). A solution-processed thin film transistor device showed a carrier mobility value of 6.0 × 10^-4 cm²/Vs with a threshold voltage of -17 V and a capacitance (C_i) of 10 nF/cm². The out-of-plane and in-plane GIXD pattern of spin-coated polymer on SiO₂ dielec. surfaces showed an amorphous halo near 2θ = 20°.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 18512-55-5. 18512-55-5 belongs to naphthyridine, auxiliary class Alkynyl,Anthracene, name is 9,10-Diethynylanthracene, and the molecular formula is C18H10, Synthetic Route of 18512-55-5.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Entwistle, Christopher D. published the artcileSyntheses, structures, two-photon absorption cross-sections and computed second hyperpolarisabilities of quadrupolar A-π-A systems containing E-dimesitylborylethenyl acceptors, Application of 9,10-Diethynylanthracene, the publication is Journal of Materials Chemistry (2009), 19(40), 7532-7544, database is CAplus.

A series of bis(E-dimesitylborylethenyl)-substituted arenes, namely arene = 1,4-benzene, 1,4-tetrafluorobenzene, 2,5-thiophene, 1,4-naphthalene, 9,10-anthracene, 4,4′-biphenyl, 2,7-fluorene, 4,4′-E-stilbene, 4,4′-tolan, 5,5′-(2,2′-bithiophene), 1,4-bis(4-phenylethynyl)benzene, 1,4-bis(4-phenylethynyl)tetrafluorobenzene and 5,5”-(2,2′:5′,2”-terthiophene), have been synthesized via hydroboration of the corresponding diethynylarenes with dimesitylborane . Their absorption and emission maxima, fluorescence lifetimes and quantum yields are reported along with the two-photon absorption (TPA) spectra and TPA cross-sections for the 5,5′-bis(E-dimesitylborylethenyl)-2,2′-bithiophene and 5,5′-bis(E-dimesitylborylethenyl)-2,2′:5′,2”-terthiophene derivatives The TPA cross-section of the latter compound of ca. 1800 GM is the largest yet reported for a 3-coordinate boron compound and is in the range of the largest values measured for quadrupolar compounds with similar conjugation lengths. The X-ray crystal structures of 1,4-benzene, 2,5-thiophene, 4,4′-biphenyl and 5,5”-(2,2′:5′,2”-terthiophene) derivatives indicate π-conjugation along the BC:C-arene-C:CB chain. Theor. studies show that the second mol. hyperpolarisabilities, γ, in each series of compounds are generally related to the HOMO energy, which itself increases with increasing donor strength of the spacer. A strong enhancement of γ is predicted as the number of thiophene rings in the spacer increases.

Journal of Materials Chemistry published new progress about 18512-55-5. 18512-55-5 belongs to naphthyridine, auxiliary class Alkynyl,Anthracene, name is 9,10-Diethynylanthracene, and the molecular formula is C18H10, Application of 9,10-Diethynylanthracene.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem