Tag: M.W=200-250

Parte, Satish published the artcileBiodegradation of sulfonated aromatic amine by Pseudomonas desmolyticum NCIM 2112, Related Products of naphthyridine, the publication is Journal of Chemical and Pharmaceutical Research (2013), 5(4), 335-339, database is CAplus.

Environmental pollutions caused by the release of wide range of compounds from various industries such as paper pulp and textiles have a serious effect on ecosystem and human health. Sulfonated azo dyes represent a large class of dyes used in textile industries. The precursors of these dyes are sulfonated aromatic amines. Release of such toxic compounds in the environment cause toxic effects on soil fertility and aquatic ecosystem. Limited attention has been paid towards the fate of sulfonated aromatic amines and substituted sulfonated aromatic amines in the environment previously. The present research work describes biodegradation of azo dye precursor 1-amino 2-naphthol 4-sulfonic acid by Pseudomonas desmolyticum NCIM 2112 which was studied by FTIR and GCMS anal. The resulting metabolites of biodegradation include propylmethane thiosulfonate and aminobenzene and they were found to be nontoxic in the environment.

Journal of Chemical and Pharmaceutical Research published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Related Products of naphthyridine.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Wang, Huiwen published the artcileMonitoring of Parathion-Methyl Based on PtNPs Combined with 4-Amino-3-Hydroxy-1-Naphthalenesulfonic Acid Fluorescent Probe and Enzyme Inhibition, SDS of cas: 116-63-2, the publication is Chemistry Africa (2022), 5(1), 99-105, database is CAplus.

In this paper, a new fluorescence anal. method was proposed to detect parathion-Me (PM) based on platinum nanoparticles (PtNPs) and 4-amino-3-hydroxy-1-naphthalenesulfonic acid (AHNSA) as fluorescent probe. AHNSA with high fluorescence could combine with PtNPs by electrostatic attraction, bringing out fluorescence quenching of AHNSA. Acetylthiocholine (ATCh) was hydrolyzed by acetylcholinesterase (AChE) to produce thiocholine, which could induce the aggregation of PtNPs by electrostatic attraction and restore the fluorescence intensity of AHNSA. However, in the presence of PM, the catalytic activity of AChE is inhibited, leading to the quenching of fluorescence of AHNSA again. Under the optimal conditions, the linear range of parathion-Me (PM) detection was 0.26-53.3 ng/mL (R2 = 0.994), and the limit of detection was 0.17 ng/mL (S/N = 3). In addition, this method has been successfully used for the determination of PM in water and food samples.

Chemistry Africa published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C7H13NO2, SDS of cas: 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Vidya, V. G. published the artcileSynthesis, characterization and applications of some azo dyes derived from various aromatic amines, Quality Control of 116-63-2, the publication is Asian Journal of Chemistry (2018), 30(9), 2049-2053, database is CAplus.

In this work, we report the synthesis of metal free dyes and their fastness properties. A series of monoazo dyes were obtained by diazotization of various aromatic primary amines and coupling with different components. One colored Schiff base derived from triethylenetetramine and N,N-dimethyl-4-aminobenzaldehyde was also synthesized. These colored compounds were characterized by FTIR, UV-visible, ¹H, ¹³C NMR and ESI mass spectroscopic methods. The dyeing performance of all the compounds were evaluated on cotton fabric. They were applied on bleached cotton fabric and their dyeing and fastness properties were assessed. The absorption spectra of the dyes are discussed with regard to their structure. The structure of colored dyes and Schiff base are proposed based on various spectroscopic data. The newly synthesized group of monoazo dyes gives shades ranging from yellow to reddish orange with good light fastness and excellent wash fastness.

Asian Journal of Chemistry published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C5H12O2, Quality Control of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Raza, Rabia published the artcileIdentification of small molecule sulfonic acids as ecto-5′-nucleotidase inhibitors, Product Details of C10H9NO4S, the publication is Medicinal Chemistry (2012), 8(6), 1133-1139, database is CAplus and MEDLINE.

Ecto-5′-Nucleotidase inhibitors have great potential as anti-tumor agents. We have investigated biochem. properties of human and rat ecto-5′-Nucleotidases and characterized 19 small mol. sulfonic acid derivatives as potential inhibitors of ecto-5′-Nucleotidases. We identified 11 potent inhibitors of human and rat ecto-5′-Nucleotidases and checked their selectivity. Compound 10 (Sodium 2,4-dinitrobenzenesulfonate) with K_i value of 0.66 μM and 19 (N-(4-sulfamoylphenylcarbamothioyl) pivalamide) with K_i value of 0.78 μM were identified as the most potent inhibitors for human and rat ecto-5′-Nucleotidase, resp. The present compounds have low mol. weights, water solubility and equal potency as compared to the reported inhibitors.

Medicinal Chemistry published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Product Details of C10H9NO4S.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Singh, Jatinder published the artcileCoordination-Driven Self-Assembly of Triazole-Based Apoptosis-Inducible Metallomacrocycles, Synthetic Route of 18512-55-5, the publication is ACS Omega (2019), 4(6), 10810-10817, database is CAplus and MEDLINE.

Ru(II)-metallomacrocycles containing 4-pyridyl-1,2,3-triazole moiety were realized by coordination-driven self-assembly. All new compounds were characterized by ESI-MS, elemental anal., ¹H and ¹³C NMR spectroscopies. The mol. structure of metallomacrocycle 8 was established by single-crystal x-ray crystallog. The anticancer activities of metallomacrocycles 5–8 were evaluated by cytotoxicity, cell cycle anal., and related protein expression. Metallomacrocycle 7 showed greatest cytotoxicity in HepG2 human hepatocellular carcinoma cells. Apoptotic HepG2 cells were analyzed when metallomacrocycle 7 was treated. The results suggest that metallomacrocycle 7 induce liver cancer cell death by increasing apoptosis and cell cycle arrest and that it has potential use as an agent for the treatment of human hepatocellular carcinoma.

ACS Omega published new progress about 18512-55-5. 18512-55-5 belongs to naphthyridine, auxiliary class Alkynyl,Anthracene, name is 9,10-Diethynylanthracene, and the molecular formula is C6H16OSi, Synthetic Route of 18512-55-5.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Gergely, Andras published the artcileCorrosion protection of cold-rolled steel with alkyd paint coatings composited with submicron-structure types polypyrrole-modified nano-size alumina and carbon nanotubes, Synthetic Route of 116-63-2, the publication is Materials Science & Engineering, B: Advanced Functional Solid-State Materials (2012), 177(18), 1571-1582, database is CAplus.

This paper is focused on studying corrosion protection of cold-rolled steel with alkyd paint coatings comprising nano-size alumina and either polystyrene-sulfonate (PSS) modified or sulfonated multi-walled carbon nanotube (MWCNT) supported polypyrrole (PPy). Single layer coatings (in thickness of 40 ± 5 μm) comprising PPy deposited alumina and PSS modified MWCNT supported PPy afforded viable protection during the 1 M sodium chloride test. The coatings containing PSS modified and weakly sulfonated MWCNTs (at volume fractions of 9.9 × 10^-4 and 2.5 × 10^-4) with PPy volume fractions of 3.5 × 10^-3 and 2.5 × 10^-3 provided effective corrosion prevention during the 1 M sodium chloride and hydrochloric acid solution tests. While inhibitor particles were characterized by IR spectroscopy, corrosion products formed at the paint-steel interface were studied by XPS. Apart from the electron microscopy observations, rheol. study of three-dimensional structure of the inhibitor particles was performed in dispersions at similar compositions to those used for the paint formulations. Thus, protection mechanism relating to both types of immersion tests is discussed in terms of properties of the inhibitor particles and their microstructure in the coatings.

Materials Science & Engineering, B: Advanced Functional Solid-State Materials published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Synthetic Route of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Shah, Maulin P. published the artcileMicrobial degradation of reactive red by Pseudomonas spp. MPS-2, Synthetic Route of 116-63-2, the publication is Journal of Bioremediation & Biodegradation (2013), 4(6), 1000197/1-1000197/7, database is CAplus.

Azo dyes are a widespread class of poorly biodegradable industrial pollutants. In anaerobic environments, azo bonds are reductively cleaved yielding carcinogenic aromatic amines, many of which are assumed to resist further metabolism by anaerobes bacteria. The latter compounds generally require aerobic conditions for their degradation A reactive group of azo dye called C.I: Reactive Red was found to be degraded using Pseudomonas spp. MPS-79 to α-ketoglutaric acid with transient accumulation of 4-aminobenzenesulfonic acid (sulphanilic acid), 4-amino, 3-hydronaphthalenesulfonic acid and 4-amino, 5-hydronaphthalene 2,7 disulfonic acid as a degradation intermediate in anaerobic facultative batch culture. Color and Total Organic Carbon (TOC) was successfully removed more than 95% and upto 50% resp. There is no significant correlation between pH and oxygen depletion since there is slightly change in pH was observed (pH from 7.21 to 7.25) though the anaerobiosis was found developed throughout the experiment (redox potential from 0.7 to 1.6 mV). The anaerobic metabolism of glucose as co-metabolite also shown to provide the electrons required for the initial reductive cleavage of the azo group. This finding suggest that it is possible to mineralize the azo dye in the environment; thereby, avoiding accumulation of toxic intermediates in the water.

Journal of Bioremediation & Biodegradation published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C14H20BClO2, Synthetic Route of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Anjali published the artcileSynthesis, characterisation, antioxidant and antimicrobial activity of isatin derivatives, Name: 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, the publication is International Research Journal of Pharmacy (2019), 10(9), 223-230, database is CAplus.

In the present study some novel Schiff bases of isatin I [R = OH, 2-O₂NC₆H₄, 2-Cl-4-O₂NC₆H₃, etc.] were synthesized by condensation of isatin mol. with anilines after performing the mol. docking and ADME prediction. Some new Schiff bases of isatin I were prepared in order to study the antibacterial, antifungal and antioxidant properties. The isatin was synthesized by Sandmeyer method and then its derivatives I were synthesized after obtaining significant results from mol. docking and ADME prediction. The structures of the synthesized compounds I were confirmed by means of IR, ¹H-NMR and elemental anal. Synthesized compounds I were screened for antioxidant activity, among which I [R = 2-Cl-4-O₂NC₆H₃] showed potent activity as antioxidant. Synthesized compounds I showed broad spectrum of antibacterial and antifungal activities.

International Research Journal of Pharmacy published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Name: 4-Amino-3-hydroxynaphthalene-1-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Kumar, Sunil published the artcileSynthesis, characterization and evaluation for anticonvulsant activity of acetylnaphthalene and substituted acetylenaphthalene derivative of heterocyclic compounds, Synthetic Route of 116-63-2, the publication is Pharma Innovation (2013), 1(11), 90-101, database is CAplus.

A series of acetyl- and acetoxynaphthalenes was prepared by Mannich reaction with secondary amines and CH₂O. In this reaction the Ac group served as he H active compound The novel compounds were tested for anticonvulsant activity using pentylenetetrazole (scPTZ) test. Some of the compounds showed significant anticonvulsant activity.

Pharma Innovation published new progress about 116-63-2. 116-63-2 belongs to naphthyridine, auxiliary class Sulfonic acid,Amine,Naphthalene,Alcohol,Organic Pigment, name is 4-Amino-3-hydroxynaphthalene-1-sulfonic acid, and the molecular formula is C10H9NO4S, Synthetic Route of 116-63-2.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem

Singh, Jatinder published the artcileCoordination-Driven Self-Assembly of Triazole-Based Apoptosis-Inducible Metallomacrocycles, Synthetic Route of 18512-55-5, the publication is ACS Omega (2019), 4(6), 10810-10817, database is CAplus and MEDLINE.

Ru(II)-metallomacrocycles containing 4-pyridyl-1,2,3-triazole moiety were realized by coordination-driven self-assembly. All new compounds were characterized by ESI-MS, elemental anal., ¹H and ¹³C NMR spectroscopies. The mol. structure of metallomacrocycle 8 was established by single-crystal x-ray crystallog. The anticancer activities of metallomacrocycles 5–8 were evaluated by cytotoxicity, cell cycle anal., and related protein expression. Metallomacrocycle 7 showed greatest cytotoxicity in HepG2 human hepatocellular carcinoma cells. Apoptotic HepG2 cells were analyzed when metallomacrocycle 7 was treated. The results suggest that metallomacrocycle 7 induce liver cancer cell death by increasing apoptosis and cell cycle arrest and that it has potential use as an agent for the treatment of human hepatocellular carcinoma.

ACS Omega published new progress about 18512-55-5. 18512-55-5 belongs to naphthyridine, auxiliary class Alkynyl,Anthracene, name is 9,10-Diethynylanthracene, and the molecular formula is C6H16OSi, Synthetic Route of 18512-55-5.

Referemce:
https://en.wikipedia.org/wiki/1,8-Naphthyridine,
1,8-Naphthyridine | C8H6N2 – PubChem